Clozapine
SIGMA/C6305
Synonym: 8-
CAS Number: 5786-21-0
Empirical Formula (Hill Notation): C18H19ClN4
Molecular Weight: 326.82
MDL Number: MFCD00153785
Linear Formula: C18H19ClN4
Product Type: Chemical
| form | powder |
| InChI | 1S/C18H19ClN4/c1-22-8-10- |
| InChI key | QZUDBNBUXVUHMW-UHFFFAOYSA |
| originator | Novartis |
| Quality Level | 300 ![]() |
| SMILES string | CN1CCN(CC1)C2=Nc3cc(Cl)cc |
| solubility | 0.1 M HCl: 30 mg/mL |
| DMSO: 4.8 mg/mL | |
| ethanol: 1 mg/mL |
| Biochem/physiol Actions: | Atypical antipsychotic compound. Selective antagonist for D4-dopamine receptor. Antagonist at 5-HT2A, 5-HT2C, 5-HT3, 5-HT6, and 5-HT7 serotonin receptors. |
| Features and Benefits: | This compound is featured on the Histamine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here . |
| Features and Benefits: | This compound was developed by Novartis . To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here . |
| Packaging: | 1 g in glass bottle |
| Packaging: | 100 mg in glass bottle |
| Packaging: | 25 mg in poly bottle |
| Symbol | ![]() GHS06,GHS08 |
| Signal word | Danger |
| Hazard statements | H301 - H341 - H361 |
| Precautionary statements | P201 - P202 - P264 - P270 - P280 - P301 + P310 |
| Hazard Codes | Xn |
| Risk Statements | 63-22-68 |
| Safety Statements | 36/37 |
| RIDADR | UN 2811 6.1 / PGIII |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| UNSPSC | 12352200 |



