Calphostin C from Cladosporium cladosporioides

SIGMA/C6303 - ≥90% (HPLC), powder

Synonym: UCN-1028c

CAS Number: 121263-19-2
Empirical Formula (Hill Notation): C₄₄H₃₈O₁₄
Molecular Weight: 790.76
MDL Number: MFCD00133155
Linear Formula: C₄₄H₃₈O₁₄
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-C6303-.1MG	0.1 mg	$467.00 1/EA		Add To Favorites
45-C6303-1MG	1 mg	$2130.00 1/EA		Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	≥90% (HPLC)
biological source	microbial (Cladosporium cladosporioides)
color	red to brown
form	powder
InChI	1S/C44H38O14/c1-20(56-43(50)22-10-8-7-9-11-22)16-25-31-32-26(17-21(2)57-44(51)58-24-14-12-23(45)13-15-24)42(55-6)40(49)34-28(47)19-30(53-4)36(38(32)34)35-29(52-3)18-27(46)33(37(31)35)39(48)41(25)54-5/h7-15,18-21,45-47H,16-17H2,1-6H3
InChI key	SRJYZPCBWDVSGO-UHFFFAOYSA-N
Quality Level	200
SMILES string	COc1cc(O)c2C(=O)C(OC)=C(CC(C)OC(=O)Oc3ccc(O)cc3)c4c5C(CC(C)OC(=O)c6ccccc6)=C(OC)C(=O)c7c(O)cc(OC)c(c57)c1c24
solubility	DMF: 1 mg/mL
	DMSO: 1 mg/mL
	ethanol: 1 mg/mL
storage temp.	−20°C

Biochem/physiol Actions:	Highly specific inhibitor of protein kinase C (IC₅₀ = 50 nM); requires light for activation. At higher concentrations (100 nM or greater), it has been shown to inhibit cell proliferation and induce apoptosis in vitro.
Features and Benefits:	This compound is featured on the Phospholipase D and PKC pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here .

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥90% (HPLC)
Storage Temp.	−20°C
UNSPSC	12352200

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