Chlorhexidine diacetate salt hydrate
SIGMA/C6143 - bis(biguanide) antimicrobial
Synonym: 1,6-Bis(N5-[p-chlorophenyl]-N1-biguanido)hexane; 1,1′-Hexamethylenebis(5-[p-chlorophenyl]biguanide)
CAS Number: 206986-79-0
Empirical Formula (Hill Notation): C22H30Cl2N10 · 2C2H4O2 · xH2O
Molecular Weight: 625.55 (anhydrous basis)
EC Number: 200-302-4
MDL Number: MFCD00012532
Linear Formula: C22H30Cl2N10 · 2C2H4O2 · xH2O
Product Type: Chemical
| antibiotic activity spectrum | Gram-negative bacteria |
| Gram-positive bacteria | |
| CMC | 0.01% (25°C)(w/v) |
| form | powder |
| InChI | 1S/C22H30Cl2N10.2C2H4O2/c |
| InChI key | WDRFFJWBUDTUCA-UHFFFAOYSA |
| mode of action | cell membrane | interferes |
| Quality Level | 200 ![]() |
| SMILES string | ClC1=CC=C(NC(NC(NCCCCCCNC |
| solubility | ethanol: 50 mg/mL |
| storage temp. | room temp |
| Application: | Used to study mechanism of membrane dysruption by bis(biguanide) molecules. |
| Biochem/physiol Actions: | Chlorhexidine is a cationic broad-spectrum antimicrobial agent belonging to the bis(biguanide) family. Its mechanism of action involves destabilization of the outer bacterial membrane. It is effective against both Gram-positive and Gram-negative bacteria. Chlorhexidine is used primarily as a topical antiseptic/disinfectant in wound healing, at catheterization sites, in various dental applications and in surgical scrubs. |
| Disclaimer: | The product is not intended for use as a biocide under global biocide regulations, including but not limited to US EPA′s Federal Insecticide Fungicide and Rodenticide Act, European Biocidal Products Regulation, Canada’s Pest Management Regulatory Agency, Turkey’s Biocidal Products Regulation, Korea’s Consumer Chemical Products and Biocide Safety Management Act (K-BPR) and others. |
| Other Notes: | Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place. |
| Packaging: | 25, 100 g in poly bottle |
| Symbol | ![]() ![]() GHS07,GHS08,GHS09 |
| Signal word | Warning |
| Hazard statements | H302 - H315 - H319 - H371 - H410 |
| Precautionary statements | P273 - P301 + P312 + P330 - P302 + P352 - P305 + P351 + P338 - P308 + P311 |
| Hazard Codes | N |
| Risk Statements | 50/53 |
| Safety Statements | 60-61 |
| RIDADR | UN 3077 9 / PGIII |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | room temp |
| UNSPSC | 51102829 |




