Synonym: (+/-)-16-(3-Chlorophenoxy)-9,11,15R-trihydroxy-17,18,19,20-tetranorprosta-5Z,13E-dien-1-oic acid sodium salt hydrate
CAS Number: 55028-72-3 (anhydrous)
Empirical Formula (Hill Notation): C22H28ClNaO6 · xH2O
Molecular Weight: 446.90 (anhydrous basis)
EC Number: 259-439-3
MDL Number: MFCD11045985
Linear Formula: C22H28ClNaO6 · xH2O
Product Type: Chemical
| assay |
≥98% (HPLC) |
| color |
light brown |
| form |
powder |
| InChI |
1S/C22H29ClO6.Na.H2O/c23-15-6-5-7-17(12-15)29-14-16(24)10-11-19-18(20(25)13-21(19)26)8-3-1-2-4-9-22(27)28;;/h1,3,5-7,10-12,16,18-21,24-26H,2,4,8-9,13-14H2,(H,27,28);;1H2/q;+1;/p-1/b3-1-,11-10+;;/t16-,18-,19-,20+,21-;;/m1../s1 |
| InChI key |
ZEQHRVULQBYULU-LPFHDDPUSA-M |
| mp |
68-70 °C |
| Quality Level |
100  |
| SMILES string |
[Na+].[H]O[H].O[C@@H](COc1cccc(Cl)c1)C=C[C@H]2[C@H](O)C[C@H](O)[C@@H]2CC=C/CCCC([O-])=O |
| solubility |
H2O: >10 mg/mL |
| storage condition |
desiccated |
| storage temp. |
−20°C |
| Application: |
(+/-)-Cloprostenol sodium salt hydrate has been used in studying its influence in oestrus synchronisation and uterine development in mice. |
| Biochem/physiol Actions: |
Cloprostenol is a potent FP prostanoid receptor agonist. |
| Biochem/physiol Actions: |
Cloprostenol is a potent FP prostanoid receptor agonist. It is 2- to 3-fold more potent than fluprostenol but less selective. Cloprostenol is similar in potency to PGF2α at EP and TP prostanoid receptors. It is used for the treatment of infertility in sows and gilts. |
| Features and Benefits: |
This compound is featured on the Prostanoid Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here . |
| General description: |
Cloprostenol is a synthetic analogue of prostaglandin F2α (PGF). Cloprostenol contributes to the induction of estrus in animals and has uterotonic activity. Cloprostenol induces abortion in animals. |
| Packaging: |
1, 5 mg in glass bottle |
| Purity |
≥98% (HPLC) |
| mp |
68-70 °C |
| Storage Temp. |
−20°C |
| UNSPSC |
12352200 |
GHS07,GHS08