Cocaine hydrochloride
SIGMA/C5776
Synonym: Ecgonine methyl ester benzoate hydrochloride
CAS Number: 53-21-4
Empirical Formula (Hill Notation): C17H21NO4 · HCl
Molecular Weight: 339.81
EC Number: 200-167-1
MDL Number: MFCD00058119
Linear Formula: C17H21NO4 · HCl
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: C5776-1G
| application(s) | forensics and toxicology |
| drug control | kontrollierte Droge in Deutschland |
| USDEA Schedule II; Home Office Schedule 2; stupéfiant (France); kontrollierte Droge in Deutschland; regulated under CDSA - not available from Sigma-Aldrich Canada; estupefaciente (Spain); Decreto Lei 15/93: Tabela IB (Portugal) | |
| form | powder |
| InChI | 1S/C17H21NO4.ClH/c1-18-12 |
| InChI key | PIQVDUKEQYOJNR-VZXSFKIWSA |
| Quality Level | 200  |
| SMILES string | Cl.COC(=O)[C@H]1[C@H](C[C |
| Application: | Cocaine hydrochloride has been used: • in saline control to study the effects of cocaine self-administration in mouse brain • as adopamine (DA), noradrenaline (NA), and serotonin (5-HT) reuptake inhibitor to evoke neurotransmitter release in artificial fish cerebrospinal fluid (aCSF) • to examine conditioning to intravenous cocaine hydrochloride |
| Biochem/physiol Actions: | Inhibits the dopamine, norepinephrine, and serotonin transporters with Kis of about 300 nM, 900 nM, and 400 nM, respectively. Unlike amphetamines, it has no effect on catecholamine release. |
| Biochem/physiol Actions: | Inhibits the dopamine, norepinephrine, and serotonin transporters. |
| Features and Benefits: | This compound is featured on the Biogenic Amine Transporters page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here . |
| Legal Information: | German Dieses Produkt fällt unter das Betäubungsmittelgesetz (BtMG). Für eine Bestellung dieses Produktes ist eine Erlaubnis nach § 3 BtMG zwingend erforderlich, es sei denn, es greift eine Ausnahme von der Erlaubnispflicht nach § 4 oder § 26 BtMG. English This product is subject to the German Narcotics Act. A permit under Section 3 of the German Narcotics Act is mandatory for ordering this product unless an exemption from the permit requirement under Section 4 or Section 26 of the German Narcotics Act applies. |
| Symbol |   GHS06,GHS08 |
| Signal word | Danger |
| Hazard statements | H300 + H330 - H336 - H361d |
| Precautionary statements | P201 - P202 - P260 - P264 - P270 - P304 + P340 + P310 |
| Hazard Codes | T |
| Risk Statements | 60-25-43 |
| Safety Statements | 53-22-36/37-45 |
| RIDADR | UN 1544PSN2 6.1 / PGIII |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| UNSPSC | 12352200 |