Conduritol B epoxide
SIGMA/C5424
Synonym: 1,2-Anhydro-myo-inositol
CAS Number: 6090-95-5
MDL Number: MFCD00077326
Product Type: Chemical
| assay | ≥95% (TLC) |
| biological source | synthetic (organic) |
| form | powder |
| InChI | 1S/C6H10O5/c7-1-2(8)4(10) |
| InChI key | ZHMWOVGZCINIHW-UHFFFAOYSA |
| Quality Level | 100  |
| SMILES string | OC1C(O)C(O)C2OC2C1O |
| solubility | water: 20 mg/mL, clear, colorless to faintly yellow |
| storage temp. | 2-8°C |
| Application: | Conduritol B epoxide has been used as an inhibitor of GBA1 to discriminate between acid β-glucosidase (GBA1) and non-lysosomal β-glucosidase (GBA2) activity in β-glucosidase activity assay. It has also been used as a selective glucocerebrosidase (GCase) inhibitor. |
| Biochem/physiol Actions: | β-Glucosidase inhibitor |
| Biochem/physiol Actions: | Conduritol B epoxide (CBE) is capable of inactivating sucrase-isomaltase irreversibly. It can be used to produce cell and animal models to study on Gaucher disease (GD) and Parkinson′s disease (PD). |
| General description: | Conduritol B epoxide (CBE) is a mix of 1-L-1,2-anhydro-myo-inosi |
| Packaging: | 5, 25 mg in glass insert |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥95% (TLC) |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352119 |