α-Cyclodextrin

SIGMA/C4680 - powder, BioReagent, suitable for cell culture, ≥98%

Synonym: α-Schardinger dextrin; Cyclohexaamylose; Cyclomaltohexaose

CAS Number: 10016-20-3
Empirical Formula (Hill Notation): C₃₆H₆₀O₃₀
Molecular Weight: 972.84
EC Number: 233-007-4
MDL Number: MFCD00078207
Linear Formula: C₃₆H₆₀O₃₀
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-C4680-1G	1 g	$57.70 1/EA	Add To Favorites
45-C4680-5G	5 g	$199.00 1/EA	Add To Favorites

This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: C4680-1G

Properties
Descriptions
Safety Info.
Basic Data

assay	≥98%
form	powder
InChI	1S/C36H60O30/c37-1-7-25-13(43)19(49)31(55-7)62-26-8(2-38)57-33(21(51)15(26)45)64-28-10(4-40)59-35(23(53)17(28)47)66-30-12(6-42)60-36(24(54)18(30)48)65-29-11(5-41)58-34(22(52)16(29)46)63-27-9(3-39)56-32(61-25)20(50)14(27)44/h7-54H,1-6H2/t7-,8-,9-,10-,11-,12-,13-,14-,15-,16-,17-,18-,19-,20-,21-,22-,23-,24-,25-,26-,27-,28-,29-,30-,31-,32-,33-,34-,35-,36-/m1/s1
InChI key	HFHDHCJBZVLPGP-RWMJIURBSA-N
mp	>278 °C (dec.) (lit.)
product line	BioReagent
Quality Level	200
shipped in	ambient
SMILES string	OC[C@H]1O[C@@H]2O[C@H]3[C@H](O)[C@@H](O)[C@H](O[C@@H]3CO)O[C@H]4[C@H](O)[C@@H](O)[C@H](O[C@@H]4CO)O[C@H]5[C@H](O)[C@@H](O)[C@H](O[C@@H]5CO)O[C@H]6[C@H](O)[C@@H](O)[C@H](O[C@@H]6CO)O[C@H]7[C@H](O)[C@@H](O)[C@H](O[C@@H]7CO)O[C@H]1[C@H](O)[C@H]2O
solubility	H₂O: 10 mg/mL
sterility	non-sterile
storage temp.	room temp
technique(s)	cell culture \| mammalian: suitable

Application:	Useful for the solubilization of nonpolar macromolecules such as fatty acids, lipids, and cholesterol for use in cell culture applications. α-Cyclodextrin has been used to solubilize odanacatib, a cathepsin K inhibitor.
Biochem/physiol Actions:	α-Cyclodextrin is found to form a firm complex with dietary fats. This way it decreases the bioavailability and absorption of fats. It is known to regulate triglyceride and leptin levels in serum. In rat models, α-Cyclodextrin is shown to induce insulin sensitivity and fecal fat excretion. Thus, α-cyclodextrin is considered to be effective for treating obesity and metabolic syndromes.
General description:	α-Cyclodextrin (α-CD) is a cyclic oligosaccharide that consists of six glucopyranose units linked by α-(1,4) bonds. α-CD acts as a soluble dietary fiber and hence it is preferred to be widely used in food industry.
Packaging:	1, 5 g in poly bottle

Symbol	GHS07
Signal word	Warning
Hazard statements	H319
Precautionary statements	P305 + P351 + P338
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥98%
mp	>278 °C (dec.) (lit.)
Storage Temp.	room temp
UNSPSC	12352201

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