Cyclobenzaprine hydrochloride
SIGMA/C4542
Synonym: 5-
CAS Number: 6202-23-9
Empirical Formula (Hill Notation): C20H21N · HCl
Molecular Weight: 311.85
EC Number: 228-264-4
MDL Number: MFCD00079039
Linear Formula: C20H21N · HCl
Product Type: Chemical
| form | powder |
| InChI | 1S/C20H21N.ClH/c1-21(2)15 |
| InChI key | VXEAYBOGHINOKW-UHFFFAOYSA |
| originator | Johnson & Johnson |
| Quality Level | 200  |
| SMILES string | Cl.CN(C)CCC=C1c2ccccc2C |
| Application: | Cyclobenzaprine hydrochloride has been used to study its effect on the muscles of dystrophin-deficient mdx5Cv mice. |
| Application: | Cyclobenzaprine hydrochloride has been used to study its effects on the muscles of dystrophin-deficient mdx5 |
| Biochem/physiol Actions: | Cyclobenzaprine hydrochloride is a type of tricyclic skeletal drug, which is commonly used as a muscle relaxant. It is very effective in treating intractable pain of cervical and lumbar origin caused by skeletal muscle spasm. cyclobenzaprine hydrochloride inhibit tonic α-mononeuronal excitation mediated by descending serotonergic systems by interacting with serotonin receptors at the spinal cord level. |
| Biochem/physiol Actions: | Skeletal muscle relaxant; 5-HT2 serotonin receptor antagonist. |
| Biochem/physiol Actions: | Skeletal muscle relaxant; reduces muscle spasm by depression of brainstem neurons; 5-HT2 serotonin receptor antagonist. |
| Features and Benefits: | This compound was developed by Johnson & Johnson . To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here . |
| General description: | Cyclobenzaprine is a tricyclic agent, which has anti-depressant and anti-cholinergic properties. It lowers the tonic somatic motor activity of motor neuron systems. Cyclobenzaprine prevents the uptake of noradrenaline. It is used to treat neck, back and myofascial pain. Cyclobenzaprine functions as a nerve impulse inhibitor. |
| Symbol |  GHS06 |
| Signal word | Danger |
| Hazard statements | H301 - H312 + H332 |
| Precautionary statements | P280 - P301 + P310 + P330 - P302 + P352 + P312 - P304 + P340 + P312 |
| Hazard Codes | Xn |
| Risk Statements | 20/21/22 |
| Safety Statements | 36 |
| RIDADR | UN 2811 6.1 / PGIII |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| UNSPSC | 12352200 |