Capreomycin sulfate from Streptomyces capreolus
SIGMA/C4142 - antibacterial peptide
CAS Number: 1405-37-4
EC Number: 215-776-8
MDL Number: MFCD00079032
Product Type: Chemical
| antibiotic activity spectrum | Gram-negative bacteria |
| Gram-positive bacteria | |
| mycobacteria | |
| form | powder |
| InChI | 1S/C24H42N14O8.H2O4S/c25- |
| InChI key | LFFNIXQXRKNZCE-UBBQZPMLSA |
| mode of action | DNA synthesis | interferes |
| Quality Level | 200 ![]() |
| SMILES string | OS(O)(=O)=O.NCCC[C@H](N)C |
| storage temp. | −20°C |
| Application: | Capreomycin is used to study bacterial ribosomal subunit interactions and translocation processes during protein synthesis. It is a second line antibiotic and is used to study multidrug-resistant tuberculosis. |
| Biochem/physiol Actions: | Capreomycin is a cyclic peptide antibiotic that is often grouped with aminoglycosides. It binds across the ribosomal interface involving 23S rRNA helix 69 (H69) and 16S rRNA helix 44 (h44). |
| Other Notes: | Keep container tightly closed in a dry and well-ventilated place. |
| Packaging: | 1, 5 g in glass bottle |
| Preparation Note: | Sparingly soluble in water. |
| Symbol | ![]() GHS07,GHS08 |
| Signal word | Danger |
| Hazard statements | H302 + H312 + H332 - H360 |
| Precautionary statements | P201 - P280 - P301 + P312 + P330 - P302 + P352 + P312 - P304 + P340 + P312 - P308 + P313 |
| Hazard Codes | T |
| Risk Statements | 61-20/21/22 |
| Safety Statements | 53-22-36/37/39-45 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 51281628 |



