Cytochrome c from pigeon breast muscle
SIGMA/C4011 - ≥95% based on Mol. Wt. 12,173 basis
CAS Number: 9007-43-6
EC Number: 232-700-9
MDL Number: MFCD00130890
Product Type: Chemical
The electron transport protein complex of the inner mitochondrial membrane
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: C4011-250MG
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: C4011-25MG
| assay | ≥95% based on Mol. Wt. 12,173 basis |
| biological source | pigeon muscle (breast) |
| form | powder |
| Quality Level | 200  |
| storage temp. | −20°C |
| technique(s) | cell culture | mammalian: suitable |
| Application: | Cytochrome c has been identified as an important mediator in apoptotic pathways. The release of mitochondrial cytochrome c into the cytoplasm stimulates apoptosis and is commonly used as an indicator of the apoptotic process in the cell. Investigation on the effect of Paris Saponin I (PS I) on human gastric carcinoma cell growth (SGC7901 cells) have shown an elevated level cytoplasmic cytochrome c. Results are an inhibition of proliferation in SGC7901 cells by inducing mitochondria-dependent apoptosis through cytochrome c. |
| Biochem/physiol Actions: | The ready fluctuation of cytochrome c within the cell between ferrous and ferric states, makes it an efficient biological electron-transporter. It plays a vital role in cellular oxidations in both plants and animals. Generally regarded as a universal catalyst of respiration, it forms the essential electron-bridge between the respirable substrates and oxygen. |
| Other Notes: | View more information on cytochrome c and electron transport at www.sigma-aldrich.com/enz. |
| Packaging: | 25, 250 mg in glass bottle |
| Preparation Note: | Prepared with acetic acid without using TCA. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥95% based on Mol. Wt. 12,173 basis |
| Storage Temp. | −20°C |
| UNSPSC | 12352202 |