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Carvedilol

SIGMA/C3993 - ≥98% (HPLC), solid

Synonym: 1-(9H-Carbazol-4-yloxy)-3-[[2-(2-methoxyphenoxy)ethyl]amino]-2-propanol; BM-14190

CAS Number: 72956-09-3
Empirical Formula (Hill Notation): C24H26N2O4
Molecular Weight: 406.47
MDL Number: MFCD00864692
Linear Formula: C24H26N2O4
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-C3993-50MG 50 mg
 $111.00
1/EA		 Add To Favorites
45-C3993-250MG 250 mg
 $476.00
1/EA		 Add To Favorites
This picture is provided solely for illustration purposes, it may have been created or edited with AI. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts C3993-50MG

 

assay ≥98% (HPLC)
color white to off-white
form solid
InChI 1S/C24H26N2O4/c1-28-21-10-4-5-11-22(21)29-14-13-25-15-17(27)16-30-23-12-6-9-20-24(23)18-7-2-3-8-19(18)26-20/h2-12,17,25-27H,13-16H2,1H3
InChI key OGHNVEJMJSYVRP-UHFFFAOYSA-N
originator GlaxoSmithKline
Quality Level 100 
SMILES string OC(COC1=CC=CC2=C1C3=C(C=CC=C3)N2)CNCCOC4=CC=CC=C4OC
solubility DMSO: >20 mg/mL
Application: Carvedilol has been used:
• as a β blocker to determine its effect on hypoxia inducible factor (HIF)-mediated erythropoiesis under hypoxia in vivo
• as a βAR antagonist for inhibition of bARs
• as a β-blocker to examine airway mechanics in fungus-challenged mice
Biochem/physiol Actions: Cavedilol is a non-selective β-adrenergic blocker with α1 blocking activity.
Biochem/physiol Actions: Cavedilol is a non-selective β-adrenergic blocker with α1 blocking activity. Carvedilol is used specifically for the treatment of heart failure and high blood pressure. It has been shown to improve left ventricular ejection fraction and may reduce mortality.
Features and Benefits: This compound is featured on the β-Adrenoceptors  page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here .
Features and Benefits: This compound was developed by GlaxoSmithKline . To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here .
Packaging: 50, 250 mg in glass bottle
Symbol GHS09  GHS09
Hazard statements H411
Precautionary statements P273
Hazard Codes N
Risk Statements 51/53
Safety Statements 61
RIDADR UN 3077 9 / PGIII
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
UNSPSC 12352200

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