Ciglitizone
SIGMA/C3974 - ≥98% (HPLC)
Synonym: (±)
CAS Number: 74772-77-3
Empirical Formula (Hill Notation): C18H23NO3S
Molecular Weight: 333.45
MDL Number: MFCD00865499
Linear Formula: C18H23NO3S
Product Type: Chemical
| assay | ≥98% (HPLC) |
| form | powder |
| InChI | 1S/C18H23NO3S/c1-18(9-3-2 |
| InChI key | YZFWTZACSRHJQD-UHFFFAOYSA |
| originator | Takeda |
| Quality Level | 100  |
| SMILES string | CC1(CCCCC1)COc2ccc(CC3SC( |
| Application: | Ciglitizone has been used as a proliferator-activated receptor γ (PPARγ) agonist: • to study its effects on cell proliferation in human melanocytes • to study its effects on pigmentation and migration of human melanocytes It also may be used to study its effects on cell cycle and apoptosis in monocytic cells. |
| Biochem/physiol Actions: | Ciglitizone belongs to the class of thiazolidinediones and is a peroxisome proliferator-activated receptor γ (PPARγ) agonist. It exhibits anti-diabetic activity. Ciglitizone has the potential to treat tumor necrosis factor α (TNFα)-related apoptosis-inducing ligand (TRAIL)-refractory high-grade urothelial cancers. |
| Features and Benefits: | This compound is a featured product for Gene Regulation research. Click here to discover more featured Gene Regulation products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm . |
| Features and Benefits: | This compound was developed by Takeda . To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here . |
| Packaging: | 5 mg in glass insert |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98% (HPLC) |
| UNSPSC | 12352200 |