CHAPSO
SIGMA/C3649 - ≥98%
Synonym: 3-
CAS Number: 82473-24-3
Empirical Formula (Hill Notation): C32H58N2O8S
Molecular Weight: 630.88
MDL Number: MFCD00081079
Linear Formula: C32H58N2O8S
Product Type: Chemical
| aggregation number | 11 |
| assay | ≥98% |
| biological source | animal |
| CMC | 8 mM (20-25°C) |
| conductivity | ≤100 μmho per cm at 24 °C (0.5 M aqueous solution) |
| description | zwitterionic |
| form | powder |
| impurities | ≤5% Water (Karl Fischer) |
| InChI | 1S/C32H58N2O8S/c1-20(7-10 |
| InChI key | GUQQBLRVXOUDTN-XOHPMCGNSA |
| mol wt | micellar avg mol wt 7000 |
| mp | 184-186 °C (lit.) |
| Quality Level | 200 ![]() |
| SMILES string | [H][C@@]12C[C@H](O)CC[C@] |
| solubility | water: soluble 10 g/L at 20 °C |
| technique(s) | protein quantification: suitable |
| transition temp | cloud point 90 °C |
| Application: | A nondenaturing zwitterionic detergent with characteristics similar to CHAPS, although it is more soluble due to a more polar head group. Useful for the solubilization of integral membrane proteins. |
| Application: | CHAPSO has been used: • in a study to assess the processes of liposome solubilization and reconstitution of two transport proteins • in a study to investigate a novel bicelle system for orienting macromolecules over a wide temperature range • as a mixture with dilauroyl phosphatidylcholine (DLPC) in solid-state nuclear magnetic resonance (NMR) technique to study membrane-associated proteins |
| General description: | CHAPSO is a non-denaturing zwitterionic bile salt derivative, derived from Chaps by the addition of a functional hydroxyl group. |
| Packaging: | 1, 5, 25 g in glass bottle |
| Packaging: | 500 mg in glass bottle |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98% |
| mp | 184-186 °C (lit.) |
| UNSPSC | 12161900 |

