Cholecystokinin (CCK) Fragment 26-33 Amide, Non-sulfated

SIGMA/C2901 - ≥95% (HPLC), powder

Synonym: CCK-8, non-sulfated

CAS Number: 25679-24-7
Empirical Formula (Hill Notation): C₄₉H₆₂N₁₀O₁₃S₂
Molecular Weight: 1063.21
MDL Number: MFCD00076488
Linear Formula: C₄₉H₆₂N₁₀O₁₃S₂
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-C2901-1MG	1 mg	$205.00 1/EA		Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	≥95% (HPLC)
form	powder
InChI	1S/C49H62N10O13S2/c1-73-18-16-34(55-47(70)37(21-28-12-14-30(60)15-13-28)58-44(67)32(50)23-41(62)63)45(68)53-26-40(61)54-38(22-29-25-52-33-11-7-6-10-31(29)33)48(71)56-35(17-19-74-2)46(69)59-39(24-42(64)65)49(72)57-36(43(51)66)20-27-8-4-3-5-9-27/h3-15,25,32,34-39,52,60H,16-24,26,50H2,1-2H3,(H2,51,66)(H,53,68)(H,54,61)(H,55,70)(H,56,71)(H,57,72)(H,58,67)(H,59,69)(H,62,63)(H,64,65)
InChI key	OIXQINQYMGNCII-UHFFFAOYSA-N
Quality Level	200
SMILES string	CSCCC(NC(=O)C(Cc1ccc(O)cc1)NC(=O)C(N)CC(O)=O)C(=O)NCC(=O)NC(Cc2c[nH]c3ccccc23)C(=O)NC(CCSC)C(=O)NC(CC(O)=O)C(=O)NC(Cc4ccccc4)C(N)=O
storage temp.	−20°C
UniProt accession no.	P06307

Amino Acid Sequence:	Asp-Tyr-Met-Gly-Trp-Met-Asp-Phe-NH2
Application:	Cholecystokinin (CCK) Fragment 26-33 Amide, Non-sulfated has been used in the specificity testing against gastrin and pepsinogen I proteins.
Biochem/physiol Actions:	Biologically inactive form of CCK-8; CCK_B/gastrin receptor agonist that has no activity at the CCK_A receptor.
Biochem/physiol Actions:	Cholecystokinin (CCK) is a 115 amino acid preprohormone and a neurotransmitter. It exists in many isoforms. The octapeptide of CCK (CCK-8S) is the most abundant form. CCK is mapped to human chromosome 3p22.1. CCK interacts with receptors of the gastrointestinal tract and nervous system. Polymorphisms in the CCK is implicated in hallucinations in patients with Parkinson′s disease. CCK plays a key role in the activation of the calcineurin-regulated nuclear factor of activated T-cells (NFATs).

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥95% (HPLC)
Storage Temp.	−20°C
UNSPSC	12352202

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