1-Cyano-4-dimethylaminopyridinium tetrafluoroborate

SIGMA/C2776 - organic cyanylating reagent

Synonym: Cyanopyridinium Agent; CDAP

CAS Number: 59016-56-7
Empirical Formula (Hill Notation): C₈H₁₀BF₄N₃
Molecular Weight: 234.99
MDL Number: MFCD00011998
Linear Formula: C₈H₁₀BF₄N₃
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-C2776-100MG	100 mg	$198.00 1/EA	Add To Favorites
45-C2776-500MG	500 mg	$668.00 1/EA	Add To Favorites

This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: C2776-100MG

12 Principles of Green Chemistry: Principle 1—Waste Prevention. This product has a smaller environmental footprint through reduction of waste in the manufacturing process.

12 Principles of Green Chemistry: Principle 4—Designing Safer Chemicals
Chemical products should be designed to affect their desired function while minimizing their toxicity.

Properties
Descriptions
Safety Info.
Basic Data

λ_max	298-302 nm (0.1 N HCl)
assay	≥97.00% (TLC)
color	white to yellow
concentration	90-100 % (w/w) (1-Cyano-4-dimethylammoniumpyridinium tetrafluoroborate)
fluorescence	(EmM at Lambda max 28.00 - 32.00)
form	powder
greener alternative category	Aligned
greener alternative product characteristics	Waste Prevention Designing Safer Chemicals Learn more about the Principles of Green Chemistry .
InChI	1S/C8H10N3.BF3.FH/c1-10(2)8-3-5-11(7-9)6-4-8;2-1(3)4;/h3-6H,1-2H3;;1H/q+1;;/p-1
InChI key	ONCRRSYBEJHQMM-UHFFFAOYSA-M
mol wt	234.99 g/mol
Quality Level	300
SMILES string	[F-].FB(F)F.CN(C)c1cc[n+](cc1)C#N
solubility	acetonitrile: 49.00-51.00 mg/mL, clear to slightly hazy, colorless to yellow
storage temp.	−20°C
sustainability	Greener Alternative Product

Application:	1-Cyano-4-dimethylaminopyridinium (CDAP) has been used in the synthesis of conjugate vaccines as a cyanylating agent. Activation of cellulose dialysis membrane for immunosensor applications used CDAP as an activation agent.
Features and Benefits:	When compared to Cyanogen Bromide (CNBr), a similar reagent, CDAP is: • Easier to use. • Can operate at lower pH levels. • Fewer side reactions. • Cyanogen Bromide is hazardous in nature.
General description:	1-Cyano-4-dimethylaminopyridinium tetrafluoroborate is an organic cyanylating agent also termed CDAP. It is a unique cystine-labeling reagent due to its reactive nature under acidic conditions. This feature provides CDAP an advantage over other sulfhydryl labeling agents, as it can avoid potential thiol-disulfide exchange.
General description:	We are committed to bringingyou greener alternative products, which adhere to one or more of the 12Principles of Greener Chemistry. 1-Cyano-4-DimethylaminopyridineTetrafluoroborate (CDAP) is a safer alternative to cyanogen bromide (CNBr) foractivating soluble polysaccharides in vaccine development. It operates at lowerpH levels, reducing toxicity and side reactions. CDAP enables quick activationfor protein-polysaccharide conjugate vaccines, bioconjugation, and drugdelivery, promoting sustainable practices in biochemistry and pharmaceuticals. Click here for more information.
Packaging:	100, 500 mg in glass bottle

Symbol	GHS07
Signal word	Warning
Hazard statements	H315 - H319 - H335
Precautionary statements	P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26-36
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥97.00% (TLC)
Storage Temp.	−20°C
UNSPSC	12352108

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