Z-Val-Ala-Asp fluoromethyl ketone

SIGMA/C2105 - powder, ≥90% (TLC)

Synonym: Z-VAD-FMK, Non-methylated

CAS Number: 161401-82-7
Empirical Formula (Hill Notation): C₂₁H₂₈FN₃O₇
Molecular Weight: 453.46
MDL Number: MFCD03452883
Linear Formula: C₂₁H₂₈FN₃O₇
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-C2105-3MG	3 mg	$676.00 1/EA		Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	≥90% (TLC)
form	powder
InChI	1S/C21H28FN3O7/c1-12(2)18(25-21(31)32-11-14-7-5-4-6-8-14)20(30)23-13(3)19(29)24-15(9-17(27)28)16(26)10-22/h4-8,12-13,15,18H,9-11H2,1-3H3,(H,23,30)(H,24,29)(H,25,31)(H,27,28)/t13-,15-,18-/m0/s1
InChI key	SUUHZYLYARUNIA-YEWWUXTCSA-N
Quality Level	200
shipped in	dry ice
SMILES string	CC(C)[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(O)=O)C(=O)CF
storage temp.	−20°C

Amino Acid Sequence:	Z-Val-Ala-Asp-OMe-FMK
Biochem/physiol Actions:	Non-methylated competitive and irreversible inhibitor of caspase-1, as well as other caspases, which can be used directly with purified enzymes. It does not require esterase to hydrolyze the O-methyl ester like the cell-permeable form, Z-Val-Ala-Asp(OMe) fluoromethyl ketone (Product Code V-116).
Features and Benefits:	This compound is featured on the Caspases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here .

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥90% (TLC)
Storage Temp.	−20°C
UNSPSC	12352209

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