Carbenicillin

SIGMA/C1613 - Ready Made Solution, 100 mg/mL in ethanol/water

Synonym: α-Carboxybenzylpenicillin solution

Empirical Formula (Hill Notation): C₁₇H₁₈N₂O₆S
Molecular Weight: 378.40
MDL Number: MFCD00242604
Linear Formula: C₁₇H₁₈N₂O₆S
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-C1613-1ML	1 mL	$226.00 1/EA	Add To Favorites

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Properties
Descriptions
Safety Info.
Basic Data

antibiotic activity spectrum	Gram-negative bacteria
	Gram-positive bacteria
concentration	100 mg/mL in ethanol/water
form	liquid
	ready-to-use solution
InChI	1S/C17H18N2O6S/c1-17(2)11(16(24)25)19-13(21)10(14(19)26-17)18-12(20)9(15(22)23)8-6-4-3-5-7-8/h3-7,9-11,14H,1-2H3,(H,18,20)(H,22,23)(H,24,25)/t9?,10-,11+,14-/m1/s1
InChI key	FPPNZSSZRUTDAP-UWFZAAFLSA-N
mode of action	cell wall synthesis \| interferes
Quality Level	200
shipped in	wet ice
SMILES string	CC1(C)S[C@@H]2[C@H](NC(=O)C(C(O)=O)c3ccccc3)C(=O)N2[C@H]1C(O)=O
solubility	ethanol: 100 mg/mL
	H₂O: 100 mg/mL
storage temp.	−20°C
suitability	suitable for testing specifications (Bacteriostatic (cell type) E. Coli DH5a, result: pass)

Application:

Carbenicillin is used for selection of Ampicillin-resistant transformed cells. It is used to study the role of penicillin-sensitive transpeptidases in the process cell wall biosynthesis.

Biochem/physiol Actions:

Carbenicillin is an ampicillin analog with structure related to benzyl penicillin. It is effective against Gram-negative bacteria and exhibits limited activity against Gram-positive bacteria. Carbenicillin binds and inhibits the enzymes involved in the synthesis of bacterial cell wall. Since carbenicillin is less sensitive to β-lactamases than ampicillin, it is effective against ampicillin-resistant bacteria. It has superior stability at low pH and acts as a selection agent. Effective concentration of carbenicillin: 50 to 100 μg/ml.

General description:

Chemical structure: ß-lactam

Other Notes:

Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage.

Packaging:

1 mL in glass bottle

Symbol	GHS02,GHS08
Signal word	Danger
Hazard statements	H226 - H317 - H334
Precautionary statements	P210 - P233 - P240 - P280 - P303 + P361 + P353 - P304 + P340 + P312
Hazard Codes	Xn
Risk Statements	10-42/43
Safety Statements	23-36/37-45
RIDADR	UN1170 - class 3 - PG 3 - Ethanol, solution
WGK Germany	WGK 2
Flash Point(F)	104.0 °F - closed cup
Flash Point(C)	40 °C - closed cup

Storage Temp.	−20°C
UNSPSC	51282404

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