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CP-55940

SIGMA/C1112 - >98% (HPLC), powder

Synonym: 5-(1,1-Dimethylheptyl)-2-[5-hydroxy-2-(3-hydroxypropyl)cyclohexyl]phenol

CAS Number: 83002-04-4
Empirical Formula (Hill Notation): C24H40O3
Molecular Weight: 376.57
MDL Number: MFCD00673965
Linear Formula: C24H40O3
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-C1112-10MG 10 mg
$332.00
1/EA
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45-C1112-50MG 50 mg
$1360.00
1/EA
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assay >98% (HPLC)
drug control regulated under CDSA - not available from Sigma-Aldrich Canada
form powder
InChI 1S/C24H40O3/c1-4-5-6-7-14-24(2,3)19-11-13-21(23(27)16-19)22-17-20(26)12-10-18(22)9-8-15-25/h11,13,16,18,20,22,25-27H,4-10,12,14-15,17H2,1-3H3/t18-,20-,22-/m1/s1
InChI key YNZFFALZMRAPHQ-SYYKKAFVSA-N
optical activity [α]/D -24 to -30°, c = 0.2 in chloroform-d
Quality Level 100 
SMILES string CCCCCCC(C)(C)c1ccc([C@@H]2C[C@H](O)CC[C@H]2CCCO)c(O)c1
solubility DMSO: 15 mg/mL
  H2O: slightly soluble
storage condition desiccated
storage temp. 2-8°C
Application: CP-55940 has been used as a cannabinoid agonists in Chinese hamster ovary (CHO) expressing cannabinoid receptor 2(CB2).
Biochem/physiol Actions: CP-55940 is a nonclassical cannabinoids (NCCs), which lack the tetrahydropyran ring. CP-55940, a derivative of CP-47,497 is enantioselective. Due to its amphipathic nature, CP-55940 tethers in biological membrane making it favourable for the cannabinoid receptor interaction. CP-55940 belongs to the cyclohexylphenol category and modulates the brain lipidome leading to dysregulation especially during adolescence. It inhibits capsaicin-evoked sensitization of nociceptive and spinal dorsal horn neurons.
Biochem/physiol Actions: CP-55940 is a selective cannabinoid receptor agonist.
Features and Benefits: This compound is featured on the Cannabinoid Receptors  page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here .
Packaging: 10, 50 mg in glass bottle
Symbol GHS07  GHS07
Signal word Warning
Hazard statements H336
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity >98% (HPLC)
Storage Temp. 2-8°C
UNSPSC 12352200

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