Chromeceptin
SIGMA/C0868 - ≥98% (HPLC), solid
Synonym: 2-
CAS Number: 331859-86-0
Empirical Formula (Hill Notation): C19H16F3N3O
Molecular Weight: 359.35
MDL Number: MFCD00815850
Linear Formula: C19H16F3N3O
Product Type: Chemical
| assay | ≥98% (HPLC) |
| color | yellow to brown |
| form | solid |
| InChI | 1S/C19H16F3N3O/c1-25(2)13 |
| InChI key | GVINXTXGDDSXFQ-UHFFFAOYSA |
| Quality Level | 100  |
| SMILES string | CN(C)c1ccc2C(c3cccc(c3)C( |
| solubility | DMSO: >20 mg/mL |
| H2O: <2 mg/mL | |
| storage temp. | −20°C |
| Biochem/physiol Actions: | Chromeceptin binds to multifunctional protein 2 (MFP-2); inhibits Insulin-like growth factor 2 (IGF2) signaling. |
| Biochem/physiol Actions: | Chromeceptin inhibits Insulin-like growth factor 2 (IGF2) signaling by a process that begins with chromeceptin binding to multifunctional protein 2 (MFP-2). This interaction stimulates the expression of IGF binding protein 1 (IGFBP-1) and suppressor of cytokine signaling-3 (SOCS-3), both of which activate signal transducers and activators of transcription 6 (STAT6) to attenuate IGF signals. |
| Features and Benefits: | This compound is featured on the InsR page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here . |
| Packaging: | 5, 25 mg in glass bottle |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98% (HPLC) |
| Storage Temp. | −20°C |
| UNSPSC | 51111800 |