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CKI-7 dihydrochloride

SIGMA/C0742 - ≥98% (HPLC), solid

Synonym: N-(2-Aminoethyl)-5-chloroisoquinoline-8-sulphonamide dihydrochloride

CAS Number: 1177141-67-1
Empirical Formula (Hill Notation): C11H12ClN3O2S · 2HCl
Molecular Weight: 358.67
MDL Number: MFCD00897689
Linear Formula: C11H12ClN3O2S · 2HCl
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-C0742-5MG 5 mg
 $233.00
1/EA		 Add To Favorites
45-C0742-25MG 25 mg
 $973.00
1/EA		 Add To Favorites

 

assay ≥98% (HPLC)
color white to light tan
form solid
InChI 1S/C11H12ClN3O2S.2ClH/c12-10-1-2-11(18(16,17)15-6-4-13)9-7-14-5-3-8(9)10;;/h1-3,5,7,15H,4,6,13H2;2*1H
InChI key JUAVTXYOCISSSL-UHFFFAOYSA-N
Quality Level 100 
SMILES string Cl[H].Cl[H].NCCNS(=O)(=O)c1ccc(Cl)c2ccncc12
solubility H2O: >5 mg/mL
storage condition desiccated
storage temp. −20°C
Biochem/physiol Actions: CKI-7 is a CK1 inhibitor; also inhibits SGK, S6K1 and MSK1.
Biochem/physiol Actions: CKI-7 is a CK1 inhibitor; also inhibits SGK, S6K1 and MSK1. CKI-7 inhibits SGK as potently as CK1. IC50 = 6 μM.
Disclaimer: Material is hygroscopic
Packaging: 5, 25 mg in glass bottle
Symbol GHS06  GHS06
Signal word Danger
Hazard statements H301
Precautionary statements P301 + P310
Hazard Codes T
Risk Statements 25
Safety Statements 45
RIDADR UN 2811 6.1 / PGIII
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
Storage Temp. −20°C
UNSPSC 12352200

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