Carmustine
SIGMA/C0400 - ≥98%
Synonym: 1,3-
CAS Number: 154-93-8
Empirical Formula (Hill Notation): C5H9Cl2N3O2
Molecular Weight: 214.05
EC Number: 205-838-2
MDL Number: MFCD00057706
Linear Formula: C5H9Cl2N3O2
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: C0400-100MG
| assay | ≥98% |
| form | (Oily liquid to amorphous solid) |
| InChI | 1S/C5H9Cl2N3O2/c6-1-3-8-5 |
| InChI key | DLGOEMSEDOSKAD-UHFFFAOYSA |
| mp | 30 °C (lit.) |
| originator | Bristol-Myers Squibb |
| Quality Level | 200  |
| SMILES string | ClCCNC(=O)N(CCCl)N=O |
| solubility | ethanol: 19.60-20.40 mg/mL, clear, pale yellow to yellow |
| storage temp. | −20°C |
| Application: | Carmustine has been used to select transduced cells expressing MGMTP140K, a foamy virus vector. It has also been used in fluorescence-activated cell sorting (FACS) assay, to test the response of cell lines to carmustine. |
| Biochem/physiol Actions: | Carmustine is a DNA alkylating agent causing DNA interstrand crosslinks. Effective against glioma and other solid tumors. |
| Features and Benefits: | This compound is a featured product for Apoptosis research. Click here to discover more featured Apoptosis products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm . |
| Features and Benefits: | This compound was developed by Bristol-Myers Squibb . To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here . |
| General description: | Carmustine is a mustard gas related β-chloro-nitrosourea compound, which is used in chemotherapy. It inhibits DNA replication and DNA transcription. |
| Packaging: | 100 mg in glass bottle |
| Packaging: | 25 mg in poly bottle |
| Symbol |   GHS06,GHS08 |
| Signal word | Danger |
| Hazard statements | H300 - H350 - H360 |
| Precautionary statements | P201 - P301 + P310 + P330 |
| Hazard Codes | T+ |
| Risk Statements | 45-46-60-61-28 |
| Safety Statements | 53-22-36/37/39-45 |
| RIDADR | UN 2811 6.1 / PGII |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98% |
| mp | 30 °C (lit.) |
| Storage Temp. | −20°C |
| UNSPSC | 12352200 |