N-Butyldeoxynojirimycin

SIGMA/B8299 - film (dried in situ)

Synonym: Miglustat; NB-DNJ

CAS Number: 72599-27-0
Empirical Formula (Hill Notation): C₁₀H₂₁NO₄
Molecular Weight: 219.28
MDL Number: MFCD00272581
Linear Formula: C₁₀H₂₁NO₄
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-B8299-1MG	1 mg	$477.00 1/EA		Add To Favorites
45-B8299-5MG	5 mg	$1760.00 1/EA		Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	≥98% (TLC)
form	film (dried in situ)
InChI	1S/C10H21NO4/c1-2-3-4-11-5-8(13)10(15)9(14)7(11)6-12/h7-10,12-15H,2-6H2,1H3/t7-,8+,9-,10-/m1/s1
InChI key	UQRORFVVSGFNRO-UTINFBMNSA-N
Quality Level	200
SMILES string	CCCCN1C[C@H](O)[C@@H](O)[C@H](O)[C@H]1CO
solubility	water: 9.80-10.20 mg/mL, clear, colorless
storage temp.	2-8°C

Application:	N-Butyldeoxynojirimycin has been used: • in the inhibition of glycolipid synthesis in neuroblastoma cells • in the inhibition the ceramide-specific glycosyltransferase in hepatocytes • in the inhibition of β-glucosidase (GBA2) using fluorescence- activity assay in human embryonic kidney (HEK293) cells.
Biochem/physiol Actions:	α-glucosidase Inhibitor
Biochem/physiol Actions:	N-Butyldeoxynojirimycin is an inhibitor of glucosyltransferase and α-glucosidases. N-Butyldeoxynojirimycin, also known as misglustat, reduces glycolipid levels by substrate reduction therapy (SRT) and is effectively used for the treatment of glycosphingolipid lysosomal storage disorder, Gaucher disease.
General description:	N-Butyldeoxynojirimycin is an alkylated product of imino sugar deoxynojirimycin.
Packaging:	1, 5 mg in glass bottle

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥98% (TLC)
Storage Temp.	2-8°C
UNSPSC	12352200

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