PiB

SIGMA/B7688 - ≥98% (HPLC)

CAS Number: 64005-90-9
Empirical Formula (Hill Notation): C₂₂H₁₈N₂O₈
Molecular Weight: 438.39
MDL Number: MFCD00333607
Linear Formula: C₂₂H₁₈N₂O₈
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-B7688-25MG	25 mg	$356.00 1/EA		Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	≥98% (HPLC)
color	white to light brown
form	powder
InChI	1S/C22H18N2O8/c1-3-31-15(25)9-23-19(27)11-5-7-13-18-14(8-6-12(17(11)18)20(23)28)22(30)24(21(13)29)10-16(26)32-4-2/h5-8H,3-4,9-10H2,1-2H3
InChI key	WNKQGFNIIHNGQM-UHFFFAOYSA-N
Quality Level	100
SMILES string	O=C(C1=C2C(C3=CC=C24)=C(C(N(CC(OCC)=O)C3=O)=O)C=C1)N(CC(OCC)=O)C4=O
solubility	DMSO: 1-2 mg/mL (warmed)
storage temp.	2-8°C

Biochem/physiol Actions:	PiB is a Pin-1 inhibitor.
Biochem/physiol Actions:	PiB is an inhibitor of the peptidylprolyl isomerase Pin-1. Inhibition of Pin-1 leads to destabilization of the transcription factor Nanog, which is required for maintenance of embryonic stem cell cultures.
Packaging:	5, 25 mg in glass bottle

Hazard Codes	N
Risk Statements	50
Safety Statements	61
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥98% (HPLC)
Storage Temp.	2-8°C
UNSPSC	12352200

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