1(S),9(R)-(−)-Bicuculline methchloride

SIGMA/B7686 - ≥97% (HPLC), powder

CAS Number: 38641-83-7
Empirical Formula (Hill Notation): C₂₁H₂₀ClNO₆
Molecular Weight: 417.84
MDL Number: MFCD00055233
Linear Formula: C₂₁H₂₀NO₆Cl
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-B7686-25MG	25 mg	$317.00 1/EA		Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	≥97% (HPLC)
form	powder
InChI	1S/C21H20NO6.ClH/c1-22(2)6-5-11-7-15-16(26-9-25-15)8-13(11)18(22)19-12-3-4-14-20(27-10-24-14)17(12)21(23)28-19;/h3-4,7-8,18-19H,5-6,9-10H2,1-2H3;1H/q+1;/p-1/t18-,19+;/m0./s1
InChI key	RLJKFAMYSYWMND-GRTNUQQKSA-M
Quality Level	100
SMILES string	[Cl-].C[N+]1(C)CCc2cc3OCOc3cc2[C@H]1[C@@H]4OC(=O)c5c6OCOc6ccc45
solubility	H₂O: >10 mg/mL
storage temp.	2-8°C

Biochem/physiol Actions:	1(S),9(R)-(−)-Bicuculline methchloride is a GABA_A receptor antagonist, which blocks Ca²⁺-activated potassium (SK) channels.
Features and Benefits:	This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm .
Features and Benefits:	This compound is featured on the GABAA Receptors and Potassium Channels pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here .
Packaging:	25, 125 mg in glass bottle

RIDADR	UN 1544PSN2 6.1 / PGIII
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥97% (HPLC)
Storage Temp.	2-8°C
UNSPSC	12352200

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