Benserazide hydrochloride
SIGMA/B7283 - ≥98% (HPLC), solid
Synonym: DL-Serine 2-
CAS Number: 14919-77-8
Empirical Formula (Hill Notation): C10H15N3O5 · HCl
Molecular Weight: 293.70
EC Number: 238-991-9
MDL Number: MFCD00078571
Linear Formula: C10H15N3O5 · HCl
Product Type: Chemical
| assay | ≥98% (HPLC) |
| biological source | synthetic |
| form | solid |
| InChI | 1S/C10H15N3O5.ClH/c11-6(4 |
| InChI key | ULFCBIUXQQYDEI-UHFFFAOYSA |
| originator | Roche |
| Quality Level | 100 ![]() |
200 ![]() |
|
| SMILES string | Cl.NC(CO)C(=O)NNCc1ccc(O) |
| solubility | H2O: 10 mg/mL |
| storage temp. | room temp |
| Application: | Benserazide has been used: • to inhibit dopa-decarboxylase • to induce dyskinesia • to test on purified bacterial TDCs to assess the extent to which it could affect bacterial decarboxylases • as a peripheral dopa decarboxylase inhibitor to treat mice |
| Biochem/physiol Actions: | Benserazide can block HK2 enzymatic activity in vitro. It is used along with levodopa to treat Parkinson′s disease. |
| Biochem/physiol Actions: | Inhibitor of |
| Features and Benefits: | This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm . |
| Features and Benefits: | This compound was developed by Roche . To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here . |
| General description: | Benserazide is a peripheral decarboxylase inhibitor. |
| Other Notes: | 2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research ![]() |
| Symbol | GHS07 |
| Signal word | Warning |
| Hazard statements | H315 - H319 - H335 |
| Precautionary statements | P302 + P352 - P305 + P351 + P338 |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 2 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98% (HPLC) |
| Storage Temp. | room temp |
| UNSPSC | 12352125 |


