Bezafibrate
SIGMA/B7273 - ≥98%, solid
Synonym: 2-
CAS Number: 41859-67-0
Empirical Formula (Hill Notation): C19H20ClNO4
Molecular Weight: 361.82
EC Number: 255-567-9
MDL Number: MFCD00078970
Linear Formula: C19H20ClNO4
Product Type: Chemical
| assay | ≥98% |
| form | solid |
| InChI | 1S/C19H20ClNO4/c1-19(2,18 |
| InChI key | IIBYAHWJQTYFKB-UHFFFAOYSA |
| originator | Roche |
| Quality Level | 200  |
| SMILES string | CC(C)(Oc1ccc(CCNC(=O)c2cc |
| solubility | deionized water: insoluble |
| DMF: soluble | |
| methanol: soluble |
| Application: | Bezafibrate has been used: • a supplement in the standard diet (SD) for mice to study its effect on diabetes • to evaluate its effect on hepatitis C virus (HCV) assembly and secretion • to evaluate its effect on gonadal steroidogenesis and spermatogenesis of zebrafish and also used as standard for HPLC |
| Biochem/physiol Actions: | Bezafibrate has the ability to repress HCV assembly and secretion. It is used to treat dyslipidemia. |
| Biochem/physiol Actions: | Bezafibrate is a peroxisome proliferator-activated receptor agonist for PPARα, PPARδ, and PPARγ. Lipoprotein lipase (LPL) activator. |
| Biochem/physiol Actions: | The peroxisome proliferator-activated receptor (PPAR) is a member of the steroid nuclear receptor superfamily. Bezafibrate is a peroxisome proliferator-activated receptor agonist for PPARα, PPARδ, and PPARγ. Lipoprotein lipase (LPL) activator. PPARgamma agonists, including Bezafibrate, have beneficial effects in the suppression of the inflammatory response during RSV infection and therefore might have clinical efficacy in the course of severe RSV-infection. |
| Features and Benefits: | This compound is a featured product for Gene Regulation research. Click here to discover more featured Gene Regulation products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm . |
| Features and Benefits: | This compound was developed by Roche . To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here . |
| Symbol |  GHS07 |
| Signal word | Warning |
| Hazard statements | H302 |
| Hazard Codes | Xn |
| Risk Statements | 22 |
| Safety Statements | 36 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98% |
| UNSPSC | 12352200 |