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Nα-Benzoyl-DL-arginine β-naphthylamide hydrochloride

SIGMA/B4750 - trypsin substrate

Synonym: BANA; Nα-Benzoyl-DL-arginine-2-naphthylamide hydrochloride

CAS Number: 913-04-2
Empirical Formula (Hill Notation): C23H25N5O2 · HCl
Molecular Weight: 439.94
EC Number: 213-015-4
MDL Number: MFCD00038940
Linear Formula: C23H25N5O2 · HCl
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-B4750-500MG 500 mg
 $96.70
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45-B4750-1G 1 g
 $140.00
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45-B4750-5G 5 g
 $465.00
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assay ≥98% (TLC)
form powder
InChI 1S/C23H25N5O2.ClH/c24-23(25)26-14-6-11-20(28-21(29)17-8-2-1-3-9-17)22(30)27-19-13-12-16-7-4-5-10-18(16)15-19;/h1-5,7-10,12-13,15,20H,6,11,14H2,(H,27,30)(H,28,29)(H4,24,25,26);1H
InChI key BNGRKDJZQIGWQF-UHFFFAOYSA-N
Quality Level 200 
SMILES string Cl[H].NC(=N)NCCCC(NC(=O)c1ccccc1)C(=O)Nc2ccc3ccccc3c2
solubility DMF: 50 mg/mL, clear, colorless to faintly yellow
storage temp. 2-8°C
Application: Nα-Benzoyl-DL-arginine β-naphthylamide hydrochloride has been used as a substrate in the BANA test to evaluate the inhibitory activity of stefin. It has also been used as a substrate for the determination of Ki values of inhibitors toward trypsin.
Biochem/physiol Actions: Nα-Benzoyl-DL-arginine β-naphthylamide hydrochloride (BANA) helps to determine the activities of cathepsin B and papain. BANA test is also useful in identifying the number of periodontal sites with periodontal pathogens. Presence of volatile sulfur compounds (VSCs), synthesized by oral bacteria in dental plaque or tongue coating can be colorimetrically confirmed by their ability to hydrolyze N-benzoyl-DL-arginine-2-naphthylamide.
General description: A chromogenic substrate for trypsin.
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (TLC)
Storage Temp. 2-8°C
UNSPSC 12352204

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