Biotin
SIGMA/B4639 - powder, BioReagent, suitable for cell culture, suitable for insect cell culture, suitable for plant cell culture, ≥99%
Synonym: D-Biotin; Bios II; Coenzyme R; Vitamin B7; Vitamin H
CAS Number: 58-85-5
Empirical Formula (Hill Notation): C10H16N2O3S
Molecular Weight: 244.31
EC Number: 200-399-3
MDL Number: MFCD00005541
Linear Formula: C10H16N2O3S
Product Type: Chemical
| assay | ≥99% |
| color | white to off-white |
| form | powder |
| InChI | 1S/C10H16N2O3S/c13-8(14)4 |
| InChI key | YBJHBAHKTGYVGT-ZKWXMUAHSA |
| mol wt | Mw 244.31 g/mol |
| mp | 231-233 °C (lit.) |
| product line | BioReagent |
| Quality Level | 200 ![]() |
| SMILES string | [H][C@]12CS[C@@H](CCCCC(O |
| solubility | H2O: 0.2 mg/mL (Solubility increases with addition of 1 N NaOH.) |
| storage temp. | 2-8°C |
| technique(s) | cell culture | insect: suitable |
| cell culture | mammalian: suitable | |
| cell culture | plant: suitable |
| Application: | Biotin has been used: • as a M199 media supplement in in vitro culture system • as a component of SATO serum free medium for the isolation of cortical oligodendrocyte precursors (OPCs) • in biochemical precursors culture for de novo fatty acid synthesis • as a component in aggregate culture media |
| Biochem/physiol Actions: | Essential vitamin that is important for amino acid and energy metabolism, and fatty acid synthesis. It is a prosthetic group in four mammalian carboxylase families and facilitates the binding and transfer of carbon dioxide. |
| General description: | Biotin is also called as B complex vitamin. It is a bicyclic compound, which has a molecular weight of 244.31 Da. Biotin serves as an important cofactor for mammalian carboxylases. It is found within the cells in free and bound pools. |
| Packaging: | 1, 5 g in poly bottle |
| Packaging: | 100, 500 mg in poly bottle |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥99% |
| mp | 231-233 °C (lit.) |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352201 |

