Bilirubin
SIGMA/B4126 - ≥98% (EmM/453 = 60), powder
Synonym: Bile pigment; Hemetoidin
CAS Number: 635-65-4
Empirical Formula (Hill Notation): C33H36N4O6
Molecular Weight: 584.66
EC Number: 211-239-7
MDL Number: MFCD00005499
Linear Formula: C33H36N4O6
Product Type: Chemical
This picture is provided solely for illustration purposes, it may have been created or edited with AI. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: B4126-1G
| assay | ≥98% (E |
| description | mixed isomers |
| form | powder |
| InChI | 1S/C33H36N4O6/c1-7-20-19( |
| InChI key | BPYKTIZUTYGOLE-IFADSCNNSA |
| Quality Level | 300  |
| SMILES string | CC1=C(C=C)C(NC1=O)=Cc2[ |
| solubility | aqueous acid: soluble |
| aqueous base: soluble | |
| benzene: soluble | |
| chloroform: soluble | |
| storage temp. | −20°C |
| Application: | Bilirubin has been used: • in phantom preparation • in in vitro experiments • in the preparation of bilirubin solutions for infusion |
| Biochem/physiol Actions: | Bilirubin has been studied for its properties as an endogenous antioxidant, such as for its capabilities to scavenge reactive oxygen species (ROS) and to inhibit NADPH-oxidase activity. It appears to function as an efficient peroxyl radical scavenger, protecting membrane lipids from oxidation by these radicals. At nanomolar concentrations it has been shown to protect neurons from oxidative damage. |
| Biochem/physiol Actions: | Well over 99% of total bilirubin is transported as a conjugate with albumin. Abnormally high levels of bilirubin can cause severe neurological damage, but mildly elevated levels are linked to protection from oxidative stress. |
| Disclaimer: | Protect from light. |
| General description: | Bilirubin, an end product of heme catabolism, forms from the breakdown of erythrocyte hemoglobin in the reticuloendothelial system. Heme oxygenase converts the heme of hemoglobin to biliverdin, and subsequently an NADPH-dependent biliverdin reductase converts biliverdin to bilirubin. Bilirubin is commonly found bound to serum albumin, when circulating in blood, in its dianion form. Bilirubin is also associated with bile salts, in its monoanion form. Disorders of hyperbilirubinemia may occur due to increased bilirubin synthesis or decreased bilirubin clearance. |
| Other Notes: | A major component of hemoglobin decomposition. The principal pigment of bile, and the yellow color in jaundice. |
| Packaging: | 1, 5 g in glass bottle |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 2 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98% (E |
| Storage Temp. | −20°C |
| UNSPSC | 12352202 |