Pentagastrin
SIGMA/B1636 - ≥95% (HPLC), powder
Synonym: Peptavlon; Petogasrin; N-t-Boc-β-Ala-Trp-Met-Asp-Phe amide
CAS Number: 5534-95-2
Empirical Formula (Hill Notation): C37H49N7O9S
Molecular Weight: 767.89
EC Number: 226-889-7
MDL Number: MFCD00076515
Linear Formula: C37H49N7O9S
Product Type: Chemical
| assay | ≥95% (HPLC) |
| color | white to off-white |
| form | powder |
| InChI | 1S/C37H49N7O9S/c1-37(2,3) |
| InChI key | NEYNJQRKHLUJRU-UHFFFAOYSA |
| Quality Level | 200 ![]() |
| SMILES string | CSCCC(NC(=O)C(Cc1c[nH]c2c |
| solubility | DMF: 20 mg/mL, clear, colorless to faint yellow or tan |
| storage condition | (Keep container tightly closed in a dry and well-ventilated place.) |
| storage temp. | −20°C |
| Amino Acid Sequence: | Boc-Bal-Trp-Met-Asp-Phe-N |
| Application: | Pentagastrin has been used to bidirectionally modulate lateral nucleus of the amygdala (LA) activity. It has also been used as a cholecystokinin-2 receptor (CCK2R) agonist to block the receptor binding for Ga-DOTA-MGS5 in AR42J rat pancreatic cell lines during cell uptake and receptor binding studies. |
| Biochem/physiol Actions: | Pentagastrin, a synthetic polypeptide is a gastrin analog. It contains the five C-terminal amino acids of gastrin. It acts as a cholecystokinin-2 (CCK2) receptor/ cholecystokinin-B (CCKB) receptor agonist. Pentagastrin stimulates the secretion of pepsin and gastric acid. It also aids in the evaluation of gastric acid secretory function. Pentagastrin exhibits panicogenic/ anxiogenic effects and thereby induces panic attacks in panic disorder (PD) patients. |
| General description: | Research area: Immunology & cytokines |
| Packaging: | 25, 100 mg in serum bottle |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥95% (HPLC) |
| Storage Temp. | −20°C |
| UNSPSC | 12352200 |

