BQ-123

SIGMA/B150 - ≥99%, sodium salt, lyophilized powder

Synonym: BQ123; Cyclo(D-Trp-D-Asp-Pro-D-Val-Leu)

CAS Number: 136553-81-6
Empirical Formula (Hill Notation): C₃₁H₄₁N₆O₇Na
Molecular Weight: 632.68
MDL Number: MFCD00133204
Linear Formula: C₃₁H₄₁N₆O₇Na
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-B150-1MG	1 mg	$477.00 1/EA		Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	≥99%
form	lyophilized powder
InChI	1S/C31H42N6O7/c1-16(2)12-21-27(40)33-22(13-18-15-32-20-9-6-5-8-19(18)20)28(41)35-23(14-25(38)39)31(44)37-11-7-10-24(37)29(42)36-26(17(3)4)30(43)34-21/h5-6,8-9,15-17,21-24,26,32H,7,10-14H2,1-4H3,(H,33,40)(H,34,43)(H,35,41)(H,36,42)(H,38,39)/t21-,22+,23+,24-,26+/m0/s1
InChI key	VYCMAAOURFJIHD-PJNXIOHISA-N
Quality Level	200
SMILES string	[H][C@@]12CCCN1C(=O)[C@@H](CC(O)=O)NC(=O)[C@@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](NC2=O)C(C)C
storage temp.	−20°C

Amino Acid Sequence:	cyclo-Asp-Pro-Val-Leu-Trp
Application:	BQ-123 has been used as a selective endothelin-A receptor antagonist to study its effects on tumor necrosis factor α (TNFα)-induced human airway smooth muscle cells (HASMCs) proliferation. It is also used as endothelin-A receptor antagonist to study its effects on TNFα-induced granulocyte–macrophage colony-stimulating factor (GM-CSF) expression.
Biochem/physiol Actions:	BQ-123 is an endothelin(Et) receptor antagonist and is exquisite for endothelin A (ETA) receptor. It is a cyclic pentapeptide.
Biochem/physiol Actions:	Selective ET_A endothelin receptor antagonist.

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥99%
Storage Temp.	−20°C
UNSPSC	12352204

Choose a favorite list for this item:

Catalog Number	Description	Price

		$

Please choose a list :

Continue Shopping

Returns/Order support

Please fill out the form below if you want to request order support from Krackeler Scientific.