Anti-IGFBP7 antibody produced in rabbit
SIGMA/AV48174 - affinity isolated antibody
Synonym: Anti-FSTL2; Anti-IGFBP-7; Anti-IGFBP-7v; Anti-Insulin-like growth factor binding protein 7; Anti-MAC25; Anti-PSF
Product Type: Chemical
Immunohistochemistry IGFBP7 Antibody: Cat. No. AV48174: Immunohistochemistry analysis of IGFBP7 in Human Lung Tissue with IGFBP7 Antibody 5.0 μg/mL. Observed Staining: Cytoplasm and membrane of pneumocytes
Immunoblotting Cell Type: fetal muscle (Cat. No. AV48174). Lanes 1. Antibody dilution (concentration) 1 μg/mL in cell type fetal muscle
Western Blotting Western Blot of IGFBP7 in Mouse Skeletal Muscle with IGFBP7 antibody at 1 μg/mL
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 29 kDa |
| NCBI accession no. | NP_001544   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | horse, human, rat, guinea pig, dog, bovine, rabbit |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunohistochemistry: suitable |
| western blot: suitable | |
| UniProt accession no. | Q16270 |
| Application: | Rabbit Anti-IGFBP7 antibody is suitable for western blot applications at a concentration of 1μg/ml. |
| Biochem/physiol Actions: | IGFBP7 contains 1 Ig-like C2-type (immunoglobulin-like) domain, 1 IGFBP N-terminal domain and 1 Kazal-like domain. It binds IGF-I and IGF-II with a relatively low affinity. IGFBP7 stimulates prostacyclin (PGI2) production. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | Insulin-like growth factor binding protein 7 (IGFBP7) is a protein that strongly binds to IGF-I and with low affinity to IGF-II. It is known to mediate cell adhesion and the production of prostacyclin. Loss of IGFBP7 expression has been associated with tumorigenesis. Rabbit Anti-IGFBP7 antibody recognizes human, canine, bovine, pig, mouse, and rat IGFBP7. |
| Immunogen: | Synthetic peptide directed towards the C terminal region of human IGFBP7 |
| Other Notes: | Synthetic peptide located within the following region: RGGPEKHEVTGWVLVSPLSKEDAGE |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |