Anti-GPT (AB1) antibody produced in rabbit
SIGMA/AV45710 - IgG fraction of antiserum
Synonym: Anti-AAT1; Anti-ALT1; Anti-GPT1; Anti-
Product Type: Chemical
Immunohistochemistry Anti-GPT (ab1): Cat. No. AV45710: Immunohistochemistry of GPT in Human Muscle tissue with GPT antibody at 4-8 μg/mL.
Immunoblotting Cell Type: fetal liver (Cat. No. AV45710). Lanes 1. Antibody dilution (concentration) 5.0 μg/mL in cell type fetal liver
| antibody form | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 55 kDa |
| NCBI accession no. | NP_005300   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | bovine, guinea pig, human, dog, mouse, rat |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunohistochemistry: suitable |
| western blot: suitable | |
| UniProt accession no. | P24298 |
| Application: | Anti-GPT (AB1) antibody produced in rabbit is suitable for western blotting at a concentration of 5.0μg/ml and for immunohistochemistry of paraffin-embedded tissue sections at a concentration of 4-8μg/ml. |
| Biochem/physiol Actions: | Glutamic-pyruvate transaminase (GPT; alanine aminotransferase, AAT1) is a cytosolic enzyme that is important for metabolism of glucose and amino acids. It catalyzes the formation of pyruvate and glutamate by reversible transmination between alanine and 2-oxoglutarate. Activity of this enzyme indicates liver injury due to drug toxicity, alcohol and infection. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Immunogen: | Synthetic peptide directed towards the N terminal region of human GPT |
| Other Notes: | Synthetic peptide located within the following region: RRVEYAVRGPIVQRALELEQELRQG |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |