Anti-PBX3 antibody produced in rabbit
SIGMA/AV32070 - IgG fraction of antiserum
Synonym: Anti-Pre-B-cell leukemia homeobox 3; Anti-RP11-336P12.1
Product Type: Chemical
Immunohistochemistry Anti-PBX3: Cat. No. AV32070: Immunohistochemistry of PBX3 in Human Kidney tissue with PBX3 antibody at 4-8 μg/mL.
Immunoblotting Cell Type: HepG2 (Cat. No. AV32070). Lanes 1. Antibody dilution (concentration) 2.5 μg/mL in cell type HepG2
| antibody form | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 47 kDa |
| NCBI accession no. | NP_006186   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | guinea pig, human, rat, mouse, bovine |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunohistochemistry: suitable |
| western blot: suitable | |
| UniProt accession no. | P40426 |
| Application: | Rabbit Anti-PBX3 antibody can be used for western blot applications at a concentration of 2.5μg/ml. |
| Biochem/physiol Actions: | PBX3 is a transcriptional activator that binds the sequence 5′-ATCAATCAA-3′. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | PBX3 is a homeobox transcription factor that shares homology with the human proto-oncogene, PBX1. It is known to enhance the transcriptional functions of HOX proteins and can also modulate developmental genes. Furthermore, PBX1 can regulate cell proliferation and has been implicated in gastric cancer. Rabbit Anti-PBX3 antibody recognizes human, mouse, rat, bovine, chicken, and zebrafish PBX3. |
| Immunogen: | Synthetic peptide directed towards the N terminal region of human PBX3 |
| Other Notes: | Synthetic peptide located within the following region: SRMLQTLAGVNLAGHSVQGGMALPP |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |