Anti-NPAS1 antibody produced in rabbit
SIGMA/AV32053 - affinity isolated antibody
Synonym: Anti-Neuronal PAS domain protein 1
Product Type: Chemical
Immunohistochemistry Anti-NPAS1: Cat. No. AV32053: Immunohistochemistry of NPAS1 in Human Stomach tissue with NPAS1 antibody at 4-8 μg/mL.
Immunoblotting Cell Type: Jurkat (Cat. No. AV32053). Lanes 1. Antibody dilution (concentration) 2.0 μg/mL in cell type Jurkat
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 63 kDa |
| NCBI accession no. | NP_002508   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | rabbit, human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunohistochemistry: suitable |
| western blot: suitable | |
| UniProt accession no. | Q99742 |
| Application: | Rabbit Anti-NPAS1 antibody can be used for western blotting at 2μg/ml. It can also be used for IHC at 4-8μg/ml, using paraffin-embedded tissues. |
| Biochem/physiol Actions: | NPAS1 is a member of the basic helix-loop-helix (bHLH)-PAS family of transcription factors. Studies of a related mouse gene suggest that it functions in neurons. The exact function of this gene is unclear, but it may play protective or modulatory roles during late embryogenesis and postnatal development. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | NPAS1 is a basic helix-loop-helix transcription factor that that regulates branching morphogenesis in mouse embryonic lung tissues. Studies in mice have reported that NPAS1 deficiency can result in behavioural and functional abnormalities. Rabbit Anti-NPAS1 antibody recognizes human, mouse, and rat NPAS1. |
| Immunogen: | Synthetic peptide directed towards the C terminal region of human NPAS1 |
| Other Notes: | Synthetic peptide located within the following region: TIRYGPAELGLVYPHLQRLGPGPAL |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |