Anti-SUPT16H antibody produced in rabbit
SIGMA/AV31526 - IgG fraction of antiserum
Synonym: Anti-CDC68; Anti-FACT; Anti-FACTP140; Anti-FLJ10857; Anti-FLJ14010; Anti-FLJ34357; Anti-SPT16/CDC68; Anti-Suppressor of Ty 16 homolog (S. cerevisiae)
Product Type: Chemical
Immunoblotting Cell Type: Jurkat (Cat. No. AV31526). Lanes 1. Antibody dilution (concentration) 1.25 μg/mL in cell type Jurkat
| antibody form | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 66 kDa |
| NCBI accession no. | NP_009123   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | rabbit, rat, human, pig, horse, dog |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | western blot: suitable |
| UniProt accession no. | Q9Y5B9 |
| Application: | Rabbit Anti-SUPT16H antibody can be used for western blot assays at a concentration of 1.25μg/ml. |
| Biochem/physiol Actions: | Transcription of protein-coding genes can be reconstituted on naked DNA with only the general transcription factors and RNA polymerase II. However, this minimal system cannot transcribe DNA packaged into chromatin, indicating that accessory factors may facilitate access to DNA. One such factor, FACT (facilitates chromatin transcription), interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT is composed of an 80 kDa subunit and a 140 kDa subunit, the latter of which is SUPT16H. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | SUPT16H is a transcription factor that interacts with RNF40. This transcription factor mediates structural changes in chromatin during DNA double strand repair. Rabbit Anti-SUPT16H antibody recognizes bovine, rat, human, zebrafish, mouse, and canine SUPT16H. |
| Immunogen: | Synthetic peptide directed towards the N terminal region of human SUPT16H |
| Other Notes: | Synthetic peptide located within the following region: ASKKKVEFLKQIANTKGNENANGAP |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |