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S-Acetylthioglycolic acid N-hydroxysuccinimide ester

SIGMA/A9043 - ≥95% (TLC), powder

Synonym: N-Succinimidyl (acetylthio)acetate; N-Succinimidyl S-acetylthioglycolate; S-Acetylthioglycolic acid NHS ester; SATA

CAS Number: 76931-93-6
Empirical Formula (Hill Notation): C8H9NO5S
Molecular Weight: 231.23
MDL Number: MFCD00036891
Linear Formula: C8H9NO5S
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-A9043-10MG 10 mg
 $49.40
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45-A9043-50MG 50 mg
 $92.80
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45-A9043-100MG 100 mg
 $155.00
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This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: A9043-100MG
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: A9043-50MG

 

assay ≥95% (TLC)
form powder
InChI 1S/C8H9NO5S/c1-5(10)15-4-8(13)14-9-6(11)2-3-7(9)12/h2-4H2,1H3
InChI key FLCQLSRLQIPNLM-UHFFFAOYSA-N
Quality Level 200 
SMILES string CC(=O)SCC(=O)ON1C(=O)CCC1=O
solubility acetonitrile: 50 mg/mL
  DMF: soluble
storage temp. −20°C
Application: Thiolating reagent for primary amines; thiol can be deprotected under mild conditions. Typically, couples initially to a molecule containing primary amine by amide bond buffered at pH 7.5. Deprotection may be accomplished with 0.05 M hydroxylamine at neutral pH. Useful for preparation of enzyme immunoconjugates and hapten carrier molecule conjugates.
Other Notes: Note that the ester couples very efficiently to primary amines compared to other thiolating reagents. In addition, this reagent will neutralize original amine positive charge.
Packaging: 10, 50, 100 mg in glass bottle
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥95% (TLC)
Storage Temp. −20°C
UNSPSC 12352100

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