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AM580

SIGMA/A8843 - ≥98% (HPLC)

Synonym: 4-[(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)carboxamido]benzoic acid

CAS Number: 102121-60-8
Empirical Formula (Hill Notation): C22H25NO3
Molecular Weight: 351.44
MDL Number: MFCD00673916
Linear Formula: C22H25NO3
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-A8843-5MG 5 mg
 $252.00
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assay ≥98% (HPLC)
form solid
InChI 1S/C22H25NO3/c1-21(2)11-12-22(3,4)18-13-15(7-10-17(18)21)19(24)23-16-8-5-14(6-9-16)20(25)26/h5-10,13H,11-12H2,1-4H3,(H,23,24)(H,25,26)
InChI key SZWKGOZKRMMLAJ-UHFFFAOYSA-N
Quality Level 200 
SMILES string CC1(C)CCC(C)(C)c2cc(ccc12)C(=O)Nc3ccc(cc3)C(O)=O
storage temp. −20°C
Application: Retinoid derivative used for gene expression studies of leukemia-retinoic acid receptor (PHL-RAR) cell line differentiation.
General description: AM580 is a retinobenzoic derivative and a RAR-α (retinoic acid receptor-α) agonist. It stimulates the maturation of granulocytes in NB4 promyelocytic leukemia cell line and APL (acute promyelocytic leukemia) blasts. AM580 suppresses endometrial cancer cell proliferation.
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
Storage Temp. −20°C
UNSPSC 12352200

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