Antifoam C Emulsion
SIGMA/A8011 - aqueous-silicone emulsion
Synonym: Antifoaming Agent Emulsion
Product Type: Chemical
| application(s) | (Supplement in culture media) |
| biological source | synthetic |
| contains | emulsifier |
| form | emulsion |
| mp | 0 °C (32 °F) |
| Quality Level | 200 ![]() |
| technique(s) | cell culture | hybridoma: suitable |
| microbiological culture: suitable |
| Application: | Antifoam C emulsion has been used: • as a supplement in RO-H2O and a chemically defined culture medium to determine volumetric mass transfer coefficient (kLa) of mammalian cell culture • as a component of feed medium, • as a steam-sterilized antifoaming agent in a biocontroller for pH-stat fed-batch cultivations • as a supplement in fed batch medium to mimic the typical large-scale cultivation conditions |
| Features and Benefits: | • Minimizes compatibility issues with biological systems • Highly effective defoamer at low concentrations • Highly effective and versatile silicone defoamer |
| General description: | Antifoam C emulsion is an aqueous emulsion containing 30% active silicone. This silicone-based antifoam emulsion consists of non-ionic emulsifiers different from those in antifoam emulsions B and Y-30. Antifoam C emulsion can be prediluted with 3-10 parts of cool water to aid in dispersion. Prediluted suspensions should be used immediately. Antifoam C emulsion is typically effective at 1-10 ppm. The flow properties of antifoam C emulsion are such that it can be pumped on an as-needed basis to a fermenter system with sufficient agitation to disperse the antifoam. Antifoam C emulsion can be used to regulate headspace foaming in mammalian cell culture bioreactors up to 30 ppm concentration. |
| Other Notes: | A 30% aqueous emulsion of polydimethylsiloxane concentrate. |
| Other Notes: | For additional information on our range of Biochemicals , please complete this form . |
| Packaging: | 250, 500 mL in poly bottle |
| Symbol | GHS07 |
| Signal word | Warning |
| Hazard statements | H319 - H335 |
| Precautionary statements | P305 + P351 + P338 |
| Hazard Codes | Xn |
| Risk Statements | 20-36/37 |
| Safety Statements | 26 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| mp | 0 °C (32 °F) |
| UNSPSC | 12161900 |


