Actinonin
SIGMA/A6671
Synonym: 3-
CAS Number: 13434-13-4
Empirical Formula (Hill Notation): C19H35N3O5
Molecular Weight: 385.50
MDL Number: MFCD00080257
Linear Formula: C19H35N3O5
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: A6671-25MG
| antibiotic activity spectrum | Gram-negative bacteria |
| Gram-positive bacteria | |
| assay | ≥98% (TLC) |
| biological source | synthetic (organic) |
| form | powder |
| InChI | 1S/C19H35N3O5/c1-4-5-6-8- |
| InChI key | XJLATMLVMSFZBN-UHFFFAOYSA |
| mode of action | enzyme | inhibits |
| Quality Level | 200  |
| SMILES string | CCCCCC(CC(=O)NO)C(=O)NC(C |
| solubility | ethanol: 50 mg/mL, clear, colorless |
| storage temp. | −20°C |
| Application: | Actinonin has been used as a control to inhibit meprin-β activity in C57BL/6 mice. It has also been used to study the high-affinity interaction of EcPDF with actinonin by 15N NMR spectroscopy and isothermal titration. |
| Biochem/physiol Actions: | Actinonin has inhibitory action against peptide deformylase (PDF). It is effective against Gram-positive and fastidious Gram-negative microorganisms. |
| Biochem/physiol Actions: | Actinonin is an inhibitor of leucine aminopeptidase. Actinonin has also been used to improve antibacterial activity and antiobesity therapeutics. |
| Features and Benefits: | This compound is featured on the Neuropeptidases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here . |
| General description: | Chemical structure: peptide |
| Packaging: | 10 mg in glass bottle |
| Packaging: | 25 mg in poly bottle |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98% (TLC) |
| Storage Temp. | −20°C |
| UNSPSC | 12352200 |