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Ampicillin trihydrate

SIGMA/A6140 - 900-1050 μg/mg anhydrous basis (HPLC)

Synonym: α-Aminobenzylpenicillin trihydrate; Aminobenzyl Penicillin; Ampicillin; D-(−)-α-Aminobenzylpenicillin

CAS Number: 7177-48-2
Empirical Formula (Hill Notation): C16H19N3O4S · 3H2O
Molecular Weight: 403.45
EC Number: 200-709-7
MDL Number: MFCD00072036
Linear Formula: C16H19N3O4S · 3H2O
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-A6140-5G 5 g
 $0.00
1/EA
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45-A6140-25G 25 g
 $152.00
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45-A6140-100G 100 g
 $0.00
1/EA
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antibiotic activity spectrum Gram-negative bacteria
  Gram-positive bacteria
concentration 900-1050 μg/mg (anhydrous, HPLC)
form powder or crystals
InChI 1S/C16H19N3O4S.3H2O/c1-16(2)11(15(22)23)19-13(21)10(14(19)24-16)18-12(20)9(17)8-6-4-3-5-7-8;;;/h3-7,9-11,14H,17H2,1-2H3,(H,18,20)(H,22,23);3*1H2/t9-,10-,11+,14-;;;/m1.../s1
InChI key RXDALBZNGVATNY-CWLIKTDRSA-N
mode of action cell wall synthesis | interferes
mp 198-200 °C (dec.) (lit.)
Quality Level 200 
SMILES string O.O.O.CC1(C)S[C@@H]2[C@H](NC(=O)[C@H](N)c3ccccc3)C(=O)N2[C@H]1C(O)=O
storage temp. 2-8°C
Application: Ampicillin Trihydrate is commonly used to select for ampicillin resistance in mutated and transformed cells.
Biochem/physiol Actions: A β-lactam antibiotic with an amino group side chain attached to the penicillin structure. Penicillin derivative that inhibits bacterial cell-wall synthesis (peptidoglycan cross-linking) by inactivating transpeptidases on the inner surface of the bacterial cell membrane. Bactericidal only to growing Escherichia coli . Mode of resistance: Cleavage of β-lactam ring of ampicillin by β-lactamase. Antimicrobial spectrum: Gram-negative and Gram-positive bacteria.
General description: Chemical structure: ß-lactam
Other Notes: Keep container tightly closed in a dry and well-ventilated place.
mp 198-200 °C (dec.) (lit.)
Storage Temp. 2-8°C
UNSPSC 51281703

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