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DL-2-Amino-5-phosphonopentanoic acid

SIGMA/A5282 - solid

Synonym: 5-Phosphono-DL-norvaline; DL-2-Amino-5-phosphonovaleric acid; AP-5; APV

CAS Number: 76326-31-3
Empirical Formula (Hill Notation): C5H12NO5P
Molecular Weight: 197.13
MDL Number: MFCD00010515
Linear Formula: C5H12NO5P
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-A5282-10MG 10 mg
 $119.00
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45-A5282-25MG 25 mg
 $306.00
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45-A5282-50MG 50 mg
 $490.00
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45-A5282-100MG 100 mg
 $913.00
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color white
form solid
InChI 1S/C5H12NO5P/c6-4(5(7)8)2-1-3-12(9,10)11/h4H,1-3,6H2,(H,7,8)(H2,9,10,11)
InChI key VOROEQBFPPIACJ-UHFFFAOYSA-N
Quality Level 200 
SMILES string NC(CCCP(O)(O)=O)C(O)=O
solubility 0.1 M NaOH: 4 mg/mL
  H2O: 5.6 mg/mL
  organic solvents: insoluble
Application: DL-2-Amino-5-phosphonopentanoic acid has been used:
• in the inactivation of N-methyl-D-aspartate (NMDA)-mediated synapses
• used in growth medium for inhibition of electrical activity in the neuronal network
• used to isolate N-methyl-D-aspartate receptors (NMDAR) or α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor (AMPAR)-mediated currents were isolated using this product
• used in double distilled water to compare its NMDA antagonistic action with that of prion protein (PrPC)
Biochem/physiol Actions: Anticonvulsant; potent and selective NMDA receptor antagonist.
Disclaimer: Hygroscopic
Other Notes: 2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research 
Packaging: 10, 25, 50, 100 mg in glass bottle
UNSPSC 12352106

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