1-Aminobenzotriazole
SIGMA/A3940
Synonym: 1-Benzotriazolamine; ABT
CAS Number: 1614-12-6
Empirical Formula (Hill Notation): C6H6N4
Molecular Weight: 134.14
MDL Number: MFCD00132902
Linear Formula: C6H6N4
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: A3940-250MG
12 Principles of Green Chemistry: Principle 1—Waste Prevention. This product has a smaller environmental footprint through reduction of waste in the manufacturing process.
12 Principles of Green Chemistry: Principle 5—Safer Solvents and Auxiliaries. This product utilizes reduced volumes of auxiliary substances that are less hazardous.
12 Principles of Green Chemistry: Principle 12—Inherently Safer Chemistry for Accident Prevention. This product utilizes safer chemistry to minimize the potential for chemical accidents, including releases, explosions and fires.
| assay | ≥98% (TLC) |
| form | powder |
| greener alternative category |  , Re-engineered |
| greener alternative product characteristics | Waste Prevention Safer Solvents and Auxiliaries Inherently Safer Chemistry for Accident Prevention Learn more about the Principles of Green Chemistry . |
| greener alternative product score | old score: 93 new score: 46 Find out more about DOZN™ Scoring |
| InChI | 1S/C6H6N4/c7-10-6-4-2-1-3 |
| InChI key | JCXKHYLLVKZPKE-UHFFFAOYSA |
| mp | 81-84 °C (lit.) |
| Quality Level | 200 |
| SMILES string | Nn1nnc2ccccc12 |
| solubility | ethanol: 49-51 mg/mL, clear, pale yellow to yellow |
| sustainability | Greener Alternative Product |
| Application: | 1-Aminobenzotriazole has been used as a cytochrome P450 inhibitor to study the effects of estrogen on H2O2-induced premature senescence of vascular smooth muscle cells from old rats It has also been used to study the estrogen receptor-mediated effects of 17β-estradiol. |
| Biochem/physiol Actions: | 1-Aminobenzotriazole (1-ABT) is used as an in vitro tool in drug discovery. It can differentiate the P450 from non-P450 enzyme systems. 1-ABT exhibits inhibitory action by covalent alteration of the heme prosthetic group in the P450 enzyme. |
| Biochem/physiol Actions: | Suicide inhibitor of cytochrome P450 and chloroperoxidase. |
| General description: | We are committed to bringing you Greener Alternative Products, which adhere to one of the four categories of Greener Alternatives . This product belongs to category of Re-engineered products, showing key improvements in Green Chemistry Principles “Waste Prevention”, “Safer Solvents and Auxiliaries” and “Inherently Safer Chemistry for Accident Prevention”. Click here to view its DOZN scorecard. |
| Packaging: | 250 mg in glass bottle |
| Packaging: | 50 mg in poly bottle |
| Symbol |  GHS07 |
| Signal word | Warning |
| Hazard statements | H315 - H319 - H335 |
| Precautionary statements | P302 + P352 - P305 + P351 + P338 |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98% (TLC) |
| mp | 81-84 °C (lit.) |
| UNSPSC | 12352200 |