5-Aminolevulinic acid hydrochloride
SIGMA/A3785 - ≥98%
Synonym: δ-Aminolevulinic acid hydrochloride; 5-
CAS Number: 5451-09-2
Empirical Formula (Hill Notation): C5H9NO3 · HCl
Molecular Weight: 167.59
EC Number: 226-679-5
MDL Number: MFCD00012869
Linear Formula: NH2CH2C(O)CH2CH2COOH · HCl
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: A3785-1G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: A3785-500MG
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: A3785-5G
| assay | ≥98% |
| form | powder |
| InChI | 1S/C5H9NO3.ClH/c6-3-4(7)1 |
| InChI key | ZLHFONARZHCSET-UHFFFAOYSA |
| mp | 150 °C |
| Quality Level | 300  |
| SMILES string | Cl[H].NCC(=O)CCC(O)=O |
| storage temp. | −20°C |
| technique(s) | ligand binding assay: suitable |
| Application: | 5-Aminolevulinic acid hydrochloride has been used to activate or inhibit heme biosynthesis in HeLa and K562 cell lines. It has also been used in photodynamic therapy for A431 tumor bearing mice. |
| Biochem/physiol Actions: | 5-Aminolevulinic acid (5-ALA) is an intermediate in heme biosynthesis and is useful in cancer treatment. It is a non-protein amino acid. 5-ALA also has applications in the field of agriculture. It is being studied as an inducing reagent for protoporphyrin IX (PPIX) dependent fluorescence diagnosis of metastatic lymph nodes. 5-ALA is used for photodynamic therapy of diseases, such as Paget’s disease and HPV infection-associated cervical condylomata acuminata. |
| Biochem/physiol Actions: | Intermediate in heme biosynthesis. |
| Packaging: | 1, 5 g in glass bottle |
| Packaging: | 500 mg in glass bottle |
| Hazard Codes | Xi |
| Risk Statements | 36/38 |
| Safety Statements | 26 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98% |
| mp | 150 °C |
| Storage Temp. | −20°C |
| UNSPSC | 12352209 |