Adenosine 5′-diphosphate sodium salt

SIGMA/A2754 - bacterial, ≥95% (HPLC)

Synonym: ADP sodium salt; ADP

CAS Number: 20398-34-9
Empirical Formula (Hill Notation): C₁₀H₁₅N₅O₁₀P₂
Molecular Weight: 427.20
Linear Formula: C₁₀H₁₅N₅O₁₀P₂
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-A2754-100MG	100 mg	$54.80 1/EA	Add To Favorites
45-A2754-500MG	500 mg	$74.00 1/EA	Add To Favorites
45-A2754-1G	1 g	$128.00 1/EA	Add To Favorites
45-A2754-5X1G	1 g	$483.00 5/EA	Add To Favorites

This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: A2754-100MG

Properties
Descriptions
Safety Info.
Basic Data

assay	≥95% (HPLC)
biological source	bacterial
form	powder
InChI	1S/C10H15N5O10P2/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(24-10)1-23-27(21,22)25-26(18,19)20/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H2,11,12,13)(H2,18,19,20)/t4-,6-,7-,10-/m1/s1
InChI key	XTWYTFMLZFPYCI-KQYNXXCUSA-N
Quality Level	300
SMILES string	[Na].Nc1ncnc2n(cnc12)C3OC(COP(O)(=O)OP(O)(O)=O)C(O)C3O
solubility	water: 50 mg/mL, clear to hazy, colorless
storage temp.	−20°C

Application:	Adenosine 5′-diphosphate sodium salt has been used:• as a positive control of platelet aggregation to analyze antiplatelet activity of purified disintegrin by aggregometery. • in the preparation of stock solution for a mito stress test. • as a positive control in flow cytometry analysis to study the effect of pentameric C-reactive protein (pCRP) and monomeric CRP (mCRP) on the CD62p (P-selectin) expression of platelets. • as a platelet agonist to stimulate platelet aggregation.
General description:	Adenosine 5′-diphosphate (ADP) is an adenine nucleotide involved in energy storage and nucleic acid metabolism via its conversion into ATP by FOF1-ATP synthases. ADP can also be obtained by adenylate monophosphate (AMP) reaction catalyzed by adenylate kinase. ADP is a platelet agonist that is secreted from platelet dense granules. It promotes platelet activation through its interaction with ADP receptors P2Y1 and P2Y12. Upon conversion of ADP to adenosine by ecto-ADPases, platelet activation is inhibited via adenosine receptors.
Packaging:	1 g in poly bottle
Packaging:	100, 500 mg in poly bottle

RIDADR	NONH for all modes of transport
WGK Germany	nwg
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥95% (HPLC)
Storage Temp.	−20°C
UNSPSC	41106305

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