Synonym: 1,1,1-Trifluoromethyl-6,9,12,15-heieicosatetraen-2-one; AACOCF3; Arach-CF3
CAS Number: 149301-79-1
Empirical Formula (Hill Notation): C21H31F3O
Molecular Weight: 356.47
MDL Number: MFCD00236427
Linear Formula: C21H31F3O
Product Type: Chemical
| assay |
≥97% (NMR) |
| color |
yellow |
| form |
oil |
| InChI |
1S/C21H31F3O/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(25)21(22,23)24/h6-7,9-10,12-13,15-16H,2-5,8,11,14,17-19H2,1H3/b7-6-,10-9-,13-12-,16-15- |
| InChI key |
PLWROONZUDKYKG-DOFZRALJSA-N |
| Quality Level |
100  |
| SMILES string |
CCCCCC=C/CC=C/CC=C/CC=C/CCCC(=O)C(F)(F)F |
| solubility |
DMSO: >5 mg/mL |
| storage condition |
desiccated |
| |
protect from light |
| |
under inert gas |
| storage temp. |
−20°C |
| Application: |
Arachidonyl trifluoromethyl ketone (AACOCF3) has been used as a anandamide degradation inhibitor to study its effects in primary astrocyte cultures. |
| Biochem/physiol Actions: |
Arachidonyl trifluoromethyl ketone (AACOCF3) plays a role in the inhibition of 12-hydroxyeicosatetraenoic acid (12-HETE) and thromboxane B2 produced by the platelets. |
| Biochem/physiol Actions: |
Inhibits anandamide hydrolysis in vitro; inhibits phospholipase A2. |
| Disclaimer: |
Hygroscopic, photosensitive, air sensitive |
| Features and Benefits: |
This compound is featured on the Phospholipase A2 page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here . |
| Packaging: |
5 mg in glass bottle |
| RIDADR |
NONH for all modes of transport |
| WGK Germany |
WGK 3 |
| Flash Point(F) |
Not applicable |
| Flash Point(C) |
Not applicable |
| Purity |
≥97% (NMR) |
| Storage Temp. |
−20°C |
| UNSPSC |
51111800 |
