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Aphidicolin from Nigrospora sphaerica

SIGMA/A0781 - ≥98% (HPLC), powder

Synonym: APC

CAS Number: 38966-21-1
Empirical Formula (Hill Notation): C20H34O4
Molecular Weight: 338.48
MDL Number: MFCD00083214
Linear Formula: C20H34O4
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-A0781-1MG 1 mg
 $146.00
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45-A0781-5MG 5 mg
 $641.00
1/EA		 Add To Favorites
45-A0781-10MG 10 mg
 $1190.00
1/EA		 Add To Favorites
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: A0781-10MG
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: A0781-1MG
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: A0781-5MG

 

antibiotic activity spectrum neoplastics
  viruses
assay ≥98% (HPLC)
color white
form powder
InChI 1S/C20H34O4/c1-17(11-21)15-4-3-13-9-14-10-19(13,7-8-20(14,24)12-22)18(15,2)6-5-16(17)23/h13-16,21-24H,3-12H2,1-2H3/t13-,14+,15-,16+,17-,18-,19-,20-/m0/s1
InChI key NOFOAYPPHIUXJR-APNQCZIXSA-N
mode of action DNA synthesis | interferes
mp 227-233 °C (lit.)
optical activity [α]27/D +12°, c = 1 in methanol(lit.)
Quality Level 300 
SMILES string [H][C@@]12CC[C@@]3([H])[C@](C)(CO)[C@H](O)CC[C@]3(C)[C@]14CC[C@](O)(CO)[C@]([H])(C2)C4
solubility DMSO: 10 mg/mL (stable at least six weeks at −20°C.)
  ethanol: 1 mg/mL (stable at least a week at 4°C.)
  H2O: insoluble
  methanol: 10 mg/mL
storage temp. 2-8°C
Biochem/physiol Actions: Aphidicolin is an antibiotic, a potent antiviral and antimitotic agent and DNA polymerase inhibitor.
Disclaimer: Estimated shelf-life is two years. For optimal stability, it should be protected from light and stored desiccated.
Features and Benefits: This compound is a featured product for Apoptosis research. Click here  to discover more featured Apoptosis products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm .
Packaging: 1, 5, 10 mg in glass bottle
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
mp 227-233 °C (lit.)
Storage Temp. 2-8°C
UNSPSC 12352200

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