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Phenylmethanesulfonyl fluoride solution

SIGMA/93482 - ~0.1 M in ethanol (T)

Synonym: Benzylsulfonyl fluoride; PMSF

CAS Number: 329-98-6
MDL Number: MFCD00007424
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-93482-50ML-F 50 mL
 $149.00
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45-93482-250ML-F 250 mL
 $590.00
1/EA		 Add To Favorites

 

biological source microbial
  synthetic
concentration ~0.1 M in ethanol (T)
density 0.797 g/mL at 20 °C
form liquid
InChI 1S/C7H7FO2S/c8-11(9,10)6-7-4-2-1-3-5-7/h1-5H,6H2
InChI key YBYRMVIVWMBXKQ-UHFFFAOYSA-N
Quality Level 100 
  200 
SMILES string FS(=O)(=O)Cc1ccccc1
storage temp. 2-8°C
Application: Phenylmethanesulfonyl fluoride solution has been used as a component in the cell lysate buffer in breast adenocarcinoma cell line, fibrosarcoma cell line and D5 hindbrain and spinal cord neural progenitors.
Biochem/physiol Actions: Administration of PMSF produces analgesia unrelated to its anticholinesterase effect, and prolongs the analagesic effect of centrally administered β-endorphin.
Biochem/physiol Actions: Phenylmethanesulfonyl fluoride (PMSF) is a serine protease inhibitor. It binds covalently to active site residue of proteases and prevents proteolytic activity. PMSF is used in cell lysate buffers during protein purification to prevent target protein degradation. PMSF effectively inhibits the naloxone-precipitated withdrawal jumping.
Density 0.797 g/mL at 20 °C
Storage Temp. 2-8°C
UNSPSC 12352202

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