Cholesteryl N-(2-dimethylaminoethyl)carbamate

SIGMA/92243 - ≥98% (TLC)

Synonym: 3β-{N-[2-(Dimethylamino)ethyl]carbamoyl}cholesterol; DC-Chol

CAS Number: 137056-72-5
Empirical Formula (Hill Notation): C₃₂H₅₆N₂O₂
Molecular Weight: 500.80
Linear Formula: C₃₂H₅₆N₂O₂
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-92243-500MG	500 mg	$603.00 1/EA		Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	≥98% (TLC)
form	powder or crystals
functional group	ester
InChI	1S/C32H56N2O2/c1-22(2)9-8-10-23(3)27-13-14-28-26-12-11-24-21-25(36-30(35)33-19-20-34(6)7)15-17-31(24,4)29(26)16-18-32(27,28)5/h11,22-23,25-29H,8-10,12-21H2,1-7H3,(H,33,35)/t23-,25?,26+,27-,28+,29+,31+,32-/m1/s1
InChI key	HIHOWBSBBDRPDW-MTIZRNOUSA-N
Quality Level	100
SMILES string	CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4CC(CC[C@]4(C)[C@H]3CC[C@]12C)OC(=O)NCCN(C)C
storage temp.	−20°C

Application:	Role of interleukin-6 in antigen-specific mucosal immunoglobulin A induction by cationic liposomes.: This study investigates the use of cholesteryl N-(2-dimethylaminoethyl)carbamate in cationic liposomes for enhancing mucosal immunoglobulin A production, highlighting its potential in vaccine development (Tada et al., 2021 ). Nasal vaccination with pneumococcal surface protein A in combination with cationic liposomes consisting of DOTAP and DC-chol confers antigen-mediated protective immunity against Streptococcus pneumoniae infections in mice.: This research demonstrates the efficacy of cholesteryl N-(2-dimethylaminoethyl)carbamate in nasal vaccines, providing a promising strategy for respiratory infection prevention (Tada et al., 2018 ).
Biochem/physiol Actions:	Cationic liposome, investigated in cancer gene therapy, as vaccine delivery system/adjuvant.
Packaging:	Bottomless glass bottle. Contents are inside inserted fused cone.

Hazard statements	H413
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥98% (TLC)
Storage Temp.	−20°C
UNSPSC	12352211

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