L-Threonine

SIGMA/89179 - BioXtra, ≥99.5% (NT)

Synonym: (2S,3R)-2-Amino-3-hydroxybutyric acid

CAS Number: 72-19-5
Empirical Formula (Hill Notation): C₄H₉NO₃
Molecular Weight: 119.12
EC Number: 200-774-1
MDL Number: MFCD00064270
Linear Formula: CH₃CH(OH)CH(NH₂)CO₂H
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-89179-10G	10 g	$103.00 1/EA	Add To Favorites
45-89179-50G	50 g	$354.00 1/EA	Add To Favorites
45-89179-250G	250 g	$963.00 1/EA	Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

anion traces	chloride (Cl^-): ≤50 mg/kg
	sulfate (SO₄^2-): ≤100 mg/kg
assay	≥99.5% (NT)
cation traces	Al: ≤5 mg/kg
	As: ≤0.1 mg/kg
	Ba: ≤5 mg/kg
	Bi: ≤5 mg/kg
	Cd: ≤5 mg/kg
	Co: ≤5 mg/kg
	Cr: ≤5 mg/kg
	Cu: ≤5 mg/kg
	Fe: ≤5 mg/kg
	K: ≤50 mg/kg
	Li: ≤5 mg/kg
	Mg: ≤5 mg/kg
	Mn: ≤5 mg/kg
	Mo: ≤5 mg/kg
	Na: ≤50 mg/kg
	NH₄⁺: ≤500 mg/kg
	Ni: ≤5 mg/kg
	Pb: ≤5 mg/kg
	Sr: ≤5 mg/kg
	Zn: ≤5 mg/kg
color	white to off-white
form	powder or crystals
ign. residue	≤0.1%
impurities	≤0.5% foreign amino acids
InChI	1S/C4H9NO3/c1-2(6)3(5)4(7)8/h2-3,6H,5H2,1H3,(H,7,8)/t2-,3+/m1/s1
InChI key	AYFVYJQAPQTCCC-GBXIJSLDSA-N
loss	≤0.1% loss on drying, 20 °C (HV)
mp	256 °C (dec.) (lit.)
optical activity	[α]20/D −28.5±0.5°, c = 5% in H₂O
product line	BioXtra
Quality Level	100
SMILES string	C[C@@H](O)[C@H](N)C(O)=O
solubility	H₂O: 50 mg/mL, clear, colorless

Application:

Reconstruction the feedback regulation of amino acid metabolism to develop a non-auxotrophic L-threonine producing Corynebacterium glutamicum.: This research utilizes L-Threonine as an internal standard for the detection and optimize the production of L-Threonine on genetically modifying Corynebacterium glutamicum aiming at more sustainable and cost-effective bio-manufacturing processes (Liu et al., 2024 ).

Threonine dehydrogenase regulates neutrophil homeostasis but not H3K4me3 levels in zebrafish.: This research utilises L-Threonine as a chemical treatment to study the enzymatic activity of threonine dehydrogenase in regulating neutrophil function in zebrafish (Li et al., 2024 ).

Other Notes:

Preparation of threonine-sepharose, assay and purification of protein kinase C; Amino acid spacing in isotachophoresis on polyacrylamide gel - a critical evaluation; Growth requirement of various microorganisms.

RIDADR	NONH for all modes of transport
WGK Germany	WGK 1
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥99.5% (NT)
mp	256 °C (dec.) (lit.)
UNSPSC	12352209

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